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Page 1
Revealing the macromolecular targets of complex natural products.
Reker D, Perna AM, Rodrigues T, Schneider P, Reutlinger M, Mönch B, Koeberle A, Lamers C, Gabler M, Steinmetz H, Müller R, Schubert-Zsilavecz M, Werz O, Schneider G. Reker D, et al. Among authors: steinmetz h. Nat Chem. 2014 Dec;6(12):1072-8. doi: 10.1038/nchem.2095. Epub 2014 Nov 2. Nat Chem. 2014. PMID: 25411885
Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic reticulum.
Scherer O, Steinmetz H, Kaether C, Weinigel C, Barz D, Kleinert H, Menche D, Müller R, Pergola C, Werz O. Scherer O, et al. Among authors: steinmetz h. Biochem Pharmacol. 2014 Oct 15;91(4):490-500. doi: 10.1016/j.bcp.2014.07.028. Epub 2014 Aug 12. Biochem Pharmacol. 2014. PMID: 25107704 Free article.
Sulfangolids, macrolide sulfate esters from Sorangium cellulosum.
Zander W, Irschik H, Augustiniak H, Herrmann M, Jansen R, Steinmetz H, Gerth K, Kessler W, Kalesse M, Höfle G, Müller R. Zander W, et al. Among authors: steinmetz h. Chemistry. 2012 May 14;18(20):6264-71. doi: 10.1002/chem.201100851. Epub 2012 Apr 4. Chemistry. 2012. PMID: 22488821
Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide initiated intramolecular Diels-Alder cycloaddition/macrolactonization.
Dehn R, Katsuyama Y, Weber A, Gerth K, Jansen R, Steinmetz H, Höfle G, Müller R, Kirschning A. Dehn R, et al. Among authors: steinmetz h. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):3882-7. doi: 10.1002/anie.201006880. Epub 2011 Mar 29. Angew Chem Int Ed Engl. 2011. PMID: 21472917 No abstract available.
494 results