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Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS. Gomez IG, et al. Among authors: portilla d. J Clin Invest. 2015 Jan;125(1):141-56. doi: 10.1172/JCI75852. Epub 2014 Nov 21. J Clin Invest. 2015. PMID: 25415439 Free PMC article.
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Chau BN, Xin C, Hartner J, Ren S, Castano AP, Linn G, Li J, Tran PT, Kaimal V, Huang X, Chang AN, Li S, Kalra A, Grafals M, Portilla D, MacKenna DA, Orkin SH, Duffield JS. Chau BN, et al. Among authors: portilla d. Sci Transl Med. 2012 Feb 15;4(121):121ra18. doi: 10.1126/scitranslmed.3003205. Sci Transl Med. 2012. PMID: 22344686 Free PMC article.
MicroRNAs as potential therapeutic targets in kidney disease.
Gomez IG, Grafals M, Portilla D, Duffield JS. Gomez IG, et al. Among authors: portilla d. J Formos Med Assoc. 2013 May;112(5):237-43. doi: 10.1016/j.jfma.2012.12.011. Epub 2013 Feb 4. J Formos Med Assoc. 2013. PMID: 23660218 Free PMC article. Review.
Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis.
Xavier S, Sahu RK, Landes SG, Yu J, Taylor RP, Ayyadevara S, Megyesi J, Stallcup WB, Duffield JS, Reis ES, Lambris JD, Portilla D. Xavier S, et al. Among authors: portilla d. Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F516-F532. doi: 10.1152/ajprenal.00604.2016. Epub 2017 Jan 4. Am J Physiol Renal Physiol. 2017. PMID: 28052876 Free PMC article.
Increased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis.
Megyesi J, Tarcsafalvi A, Li S, Hodeify R, Seng NS, Portilla D, Price PM. Megyesi J, et al. Among authors: portilla d. Am J Physiol Renal Physiol. 2015 Jan 15;308(2):F122-30. doi: 10.1152/ajprenal.00489.2014. Epub 2014 Nov 26. Am J Physiol Renal Physiol. 2015. PMID: 25428126 Free PMC article.
Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury.
Li S, Nagothu K, Ranganathan G, Ali SM, Shank B, Gokden N, Ayyadevara S, Megyesi J, Olivecrona G, Chugh SS, Kersten S, Portilla D. Li S, et al. Among authors: portilla d. Am J Physiol Renal Physiol. 2012 Aug 1;303(3):F437-48. doi: 10.1152/ajprenal.00111.2012. Epub 2012 May 23. Am J Physiol Renal Physiol. 2012. PMID: 22622461 Free PMC article.
78 results