Xin C - Search Results

1

Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.

Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS. Gomez IG, et al. Among authors: xin c. J Clin Invest. 2015 Jan;125(1):141-56. doi: 10.1172/JCI75852. Epub 2014 Nov 21. J Clin Invest. 2015. PMID: 25415439 Free PMC article.

2

MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.

Chau BN, Xin C, Hartner J, Ren S, Castano AP, Linn G, Li J, Tran PT, Kaimal V, Huang X, Chang AN, Li S, Kalra A, Grafals M, Portilla D, MacKenna DA, Orkin SH, Duffield JS. Chau BN, et al. Among authors: xin c. Sci Transl Med. 2012 Feb 15;4(121):121ra18. doi: 10.1126/scitranslmed.3003205. Sci Transl Med. 2012. PMID: 22344686 Free PMC article.

3

Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis.

Nakagawa N, Xin C, Roach AM, Naiman N, Shankland SJ, Ligresti G, Ren S, Szak S, Gomez IG, Duffield JS. Nakagawa N, et al. Among authors: xin c. Kidney Int. 2015 Jun;87(6):1125-40. doi: 10.1038/ki.2014.406. Epub 2015 Feb 4. Kidney Int. 2015. PMID: 25651362 Free PMC article.

4

A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation.

Ren S, Xin C, Pfeilschifter J, Huwiler A. Ren S, et al. Among authors: xin c. Cell Physiol Biochem. 2010;26(1):97-104. doi: 10.1159/000315110. Epub 2010 May 18. Cell Physiol Biochem. 2010. PMID: 20502009 Free article.

5

Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1beta-induced prostaglandin E2 formation.

Xin C, Ren S, Eberhardt W, Pfeilschifter J, Huwiler A. Xin C, et al. J Lipid Res. 2007 Sep;48(9):1985-96. doi: 10.1194/jlr.M700077-JLR200. Epub 2007 Jun 25. J Lipid Res. 2007. PMID: 17592175 Free article.

6

Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells.

Xin C, Ren S, Pfeilschifter J, Huwiler A. Xin C, et al. Br J Pharmacol. 2004 Nov;143(5):581-9. doi: 10.1038/sj.bjp.0705980. Epub 2004 Oct 4. Br J Pharmacol. 2004. PMID: 15466446 Free PMC article.

7

The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells.

Xin C, Ren S, Eberhardt W, Pfeilschifter J, Huwiler A. Xin C, et al. Br J Pharmacol. 2006 Jan;147(2):164-74. doi: 10.1038/sj.bjp.0706452. Br J Pharmacol. 2006. PMID: 16299553 Free PMC article.

8

Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury.

Schrimpf C, Xin C, Campanholle G, Gill SE, Stallcup W, Lin SL, Davis GE, Gharib SA, Humphreys BD, Duffield JS. Schrimpf C, et al. Among authors: xin c. J Am Soc Nephrol. 2012 May;23(5):868-83. doi: 10.1681/ASN.2011080851. Epub 2012 Mar 1. J Am Soc Nephrol. 2012. PMID: 22383695 Free PMC article.

9

Interleukin-1beta inhibits ATP-induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide.

Rölz W, Xin C, Ren S, Pfeilschifter J, Huwiler A. Rölz W, et al. Among authors: xin c. Br J Pharmacol. 2003 Feb;138(3):461-8. doi: 10.1038/sj.bjp.0705064. Br J Pharmacol. 2003. PMID: 12569071 Free PMC article.

10

Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.

Ren S, Babelova A, Moreth K, Xin C, Eberhardt W, Doller A, Pavenstädt H, Schaefer L, Pfeilschifter J, Huwiler A. Ren S, et al. Among authors: xin c. Kidney Int. 2009 Oct;76(8):857-67. doi: 10.1038/ki.2009.297. Epub 2009 Aug 5. Kidney Int. 2009. PMID: 19657322 Free article.

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