Lai L - Search Results

1

Modeling the mitotic regulatory network identifies highly efficient anti-cancer drug combinations.

Wu Y, Zhuo X, Dai Z, Guo X, Wang Y, Zhang C, Lai L. Wu Y, et al. Among authors: lai l. Mol Biosyst. 2015 Feb;11(2):497-505. doi: 10.1039/c4mb00610k. Mol Biosyst. 2015. PMID: 25418836

2

Modulating the substrate specificity of LTA4H aminopeptidase by using chemical compounds and small-molecule-guided mutagenesis.

Jiang X, Zhou L, Wu Y, Wei D, Sun C, Jia J, Liu Y, Lai L. Jiang X, et al. Among authors: lai l. Chembiochem. 2010 May 17;11(8):1120-8. doi: 10.1002/cbic.200900788. Chembiochem. 2010. PMID: 20432426

3

Discovery of dual target inhibitors against cyclooxygenases and leukotriene A4 hydrolyase.

Chen Z, Wu Y, Liu Y, Yang S, Chen Y, Lai L. Chen Z, et al. Among authors: lai l. J Med Chem. 2011 May 26;54(10):3650-60. doi: 10.1021/jm200063s. Epub 2011 May 4. J Med Chem. 2011. PMID: 21542630

4

Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A₂ inhibitors.

Wu Y, Chen Z, Liu Y, Yu L, Zhou L, Yang S, Lai L. Wu Y, et al. Among authors: lai l. Bioorg Med Chem. 2011 Jun 1;19(11):3361-6. doi: 10.1016/j.bmc.2011.04.039. Epub 2011 Apr 22. Bioorg Med Chem. 2011. PMID: 21555224

5

Microsomal prostaglandin E synthase-1 exhibits one-third-of-the-sites reactivity.

He S, Wu Y, Yu D, Lai L. He S, et al. Among authors: lai l. Biochem J. 2011 Nov 15;440(1):13-21. doi: 10.1042/BJ20110977. Biochem J. 2011. PMID: 21797823

6

Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors.

Wu Y, He C, Gao Y, He S, Liu Y, Lai L. Wu Y, et al. Among authors: lai l. J Med Chem. 2012 Mar 22;55(6):2597-605. doi: 10.1021/jm201497k. Epub 2012 Mar 1. J Med Chem. 2012. PMID: 22380511

7

Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network.

He C, Wu Y, Lai Y, Cai Z, Liu Y, Lai L. He C, et al. Among authors: lai y, lai l. Mol Biosyst. 2012 Apr;8(5):1585-94. doi: 10.1039/c2mb05503a. Epub 2012 Mar 26. Mol Biosyst. 2012. PMID: 22446875

8

A comprehensive analysis of the influence of drug binding kinetics on drug action at molecular and systems levels.

Yin N, Pei J, Lai L. Yin N, et al. Among authors: lai l. Mol Biosyst. 2013 Jun;9(6):1381-9. doi: 10.1039/c3mb25471b. Epub 2013 Mar 11. Mol Biosyst. 2013. PMID: 23478789

9

Understanding traditional Chinese medicine anti-inflammatory herbal formulae by simulating their regulatory functions in the human arachidonic acid metabolic network.

Gu S, Yin N, Pei J, Lai L. Gu S, et al. Among authors: lai l. Mol Biosyst. 2013 Jul;9(7):1931-8. doi: 10.1039/c3mb25605g. Epub 2013 Apr 23. Mol Biosyst. 2013. PMID: 23612801

10

Understanding molecular mechanisms of traditional Chinese medicine for the treatment of influenza viruses infection by computational approaches.

Gu S, Yin N, Pei J, Lai L. Gu S, et al. Among authors: lai l. Mol Biosyst. 2013 Nov;9(11):2696-700. doi: 10.1039/c3mb70268e. Mol Biosyst. 2013. PMID: 23986228

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