The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.
Shewell LK, Harvey RM, Higgins MA, Day CJ, Hartley-Tassell LE, Chen AY, Gillen CM, James DB, Alonzo F 3rd, Torres VJ, Walker MJ, Paton AW, Paton JC, Jennings MP.
Shewell LK, et al. Among authors: paton aw, paton jc.
Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5312-20. doi: 10.1073/pnas.1412703111. Epub 2014 Nov 24.
Proc Natl Acad Sci U S A. 2014.
PMID: 25422425
Free PMC article.