Salvemini D - Search Results

1

In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists.

Tosh DK, Finley A, Paoletta S, Moss SM, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA. Tosh DK, et al. Among authors: salvemini d. J Med Chem. 2014 Dec 11;57(23):9901-14. doi: 10.1021/jm501021n. Epub 2014 Nov 25. J Med Chem. 2014. PMID: 25422861 Free PMC article.

2

Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.

Doyle T, Finley A, Chen Z, Salvemini D. Doyle T, et al. Among authors: salvemini d. Pain. 2011 Mar;152(3):643-648. doi: 10.1016/j.pain.2010.12.011. Epub 2011 Jan 15. Pain. 2011. PMID: 21239112 Free PMC article.

3

Retooling manganese(III) porphyrin-based peroxynitrite decomposition catalysts for selectivity and oral activity: a potential new strategy for treating chronic pain.

Rausaria S, Ghaffari MM, Kamadulski A, Rodgers K, Bryant L, Chen Z, Doyle T, Shaw MJ, Salvemini D, Neumann WL. Rausaria S, et al. Among authors: salvemini d. J Med Chem. 2011 Dec 22;54(24):8658-69. doi: 10.1021/jm201233r. Epub 2011 Nov 22. J Med Chem. 2011. PMID: 22082008 Free PMC article.

4

Controlling murine and rat chronic pain through A3 adenosine receptor activation.

Chen Z, Janes K, Chen C, Doyle T, Bryant L, Tosh DK, Jacobson KA, Salvemini D. Chen Z, et al. Among authors: salvemini d. FASEB J. 2012 May;26(5):1855-65. doi: 10.1096/fj.11-201541. Epub 2012 Feb 17. FASEB J. 2012. PMID: 22345405 Free PMC article.

5

Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism.

Finley A, Chen Z, Esposito E, Cuzzocrea S, Sabbadini R, Salvemini D. Finley A, et al. Among authors: salvemini d. PLoS One. 2013;8(1):e55255. doi: 10.1371/journal.pone.0055255. Epub 2013 Jan 25. PLoS One. 2013. PMID: 23372844 Free PMC article.

6

Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain.

Paoletta S, Tosh DK, Finley A, Gizewski ET, Moss SM, Gao ZG, Auchampach JA, Salvemini D, Jacobson KA. Paoletta S, et al. Among authors: salvemini d. J Med Chem. 2013 Jul 25;56(14):5949-63. doi: 10.1021/jm4007966. Epub 2013 Jul 3. J Med Chem. 2013. PMID: 23789857 Free PMC article.

7

Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners.

Paoletta S, Tosh DK, Salvemini D, Jacobson KA. Paoletta S, et al. Among authors: salvemini d. PLoS One. 2014 May 23;9(5):e97858. doi: 10.1371/journal.pone.0097858. eCollection 2014. PLoS One. 2014. PMID: 24859150 Free PMC article.

8

Extended N(6) substitution of rigid C2-arylethynyl nucleosides for exploring the role of extracellular loops in ligand recognition at the A3 adenosine receptor.

Tosh DK, Paoletta S, Chen Z, Moss SM, Gao ZG, Salvemini D, Jacobson KA. Tosh DK, et al. Among authors: salvemini d. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3302-6. doi: 10.1016/j.bmcl.2014.06.006. Epub 2014 Jun 11. Bioorg Med Chem Lett. 2014. PMID: 24969016 Free PMC article.

9

Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy.

Janes K, Wahlman C, Little JW, Doyle T, Tosh DK, Jacobson KA, Salvemini D. Janes K, et al. Among authors: salvemini d. Brain Behav Immun. 2015 Feb;44:91-9. doi: 10.1016/j.bbi.2014.08.010. Epub 2014 Sep 8. Brain Behav Immun. 2015. PMID: 25220279 Free PMC article.

10

A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.

Janes K, Esposito E, Doyle T, Cuzzocrea S, Tosh DK, Jacobson KA, Salvemini D. Janes K, et al. Among authors: salvemini d. Pain. 2014 Dec;155(12):2560-2567. doi: 10.1016/j.pain.2014.09.016. Epub 2014 Sep 19. Pain. 2014. PMID: 25242567 Free PMC article.

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