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7,238 results

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Page 1
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy.
Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, D'Andrea A, Chen CC. Nitta M, et al. Among authors: chen cc. PLoS One. 2010 May 24;5(5):e10767. doi: 10.1371/journal.pone.0010767. PLoS One. 2010. PMID: 20532243 Free PMC article.
Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma.
Li J, Zhu S, Kozono D, Ng K, Futalan D, Shen Y, Akers JC, Steed T, Kushwaha D, Schlabach M, Carter BS, Kwon CH, Furnari F, Cavenee W, Elledge S, Chen CC. Li J, et al. Among authors: chen cc. Oncotarget. 2014 Feb 28;5(4):882-93. doi: 10.18632/oncotarget.1801. Oncotarget. 2014. PMID: 24658464 Free PMC article.
A functional screen identifies miRs that induce radioresistance in glioblastomas.
Moskwa P, Zinn PO, Choi YE, Shukla SA, Fendler W, Chen CC, Lu J, Golub TR, Hjelmeland A, Chowdhury D. Moskwa P, et al. Among authors: chen cc. Mol Cancer Res. 2014 Dec;12(12):1767-78. doi: 10.1158/1541-7786.MCR-14-0268. Epub 2014 Sep 25. Mol Cancer Res. 2014. PMID: 25256711 Free PMC article.
Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas.
Li J, Taich ZJ, Goyal A, Gonda D, Akers J, Adhikari B, Patel K, Vandenberg S, Yan W, Bao Z, Carter BS, Wang R, Mao Y, Jiang T, Chen CC. Li J, et al. Among authors: chen cc. Oncotarget. 2014 Sep 15;5(17):7342-56. doi: 10.18632/oncotarget.2350. Oncotarget. 2014. PMID: 25277177 Free PMC article.
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.
Shen Y, Li J, Nitta M, Futalan D, Steed T, Treiber JM, Taich Z, Stevens D, Wykosky J, Chen HZ, Carter BS, Becher OJ, Kennedy R, Esashi F, Sarkaria JN, Furnari FB, Cavenee WK, Desai A, Chen CC. Shen Y, et al. Among authors: chen cc, chen hz. Oncotarget. 2015 May 20;6(14):11751-67. doi: 10.18632/oncotarget.3996. Oncotarget. 2015. PMID: 26059434 Free PMC article.
Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.
Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR, Chen CC. Kozono D, et al. Among authors: chen cc. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4055-64. doi: 10.1073/pnas.1501967112. Epub 2015 Jul 9. Proc Natl Acad Sci U S A. 2015. PMID: 26159421 Free PMC article.
Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity.
Zanca C, Villa GR, Benitez JA, Thorne AH, Koga T, D'Antonio M, Ikegami S, Ma J, Boyer AD, Banisadr A, Jameson NM, Parisian AD, Eliseeva OV, Barnabe GF, Liu F, Wu S, Yang H, Wykosky J, Frazer KA, Verkhusha VV, Isaguliants MG, Weiss WA, Gahman TC, Shiau AK, Chen CC, Mischel PS, Cavenee WK, Furnari FB. Zanca C, et al. Among authors: chen cc. Genes Dev. 2017 Jun 15;31(12):1212-1227. doi: 10.1101/gad.300079.117. Epub 2017 Jul 19. Genes Dev. 2017. PMID: 28724615 Free PMC article.
7,238 results