Doherty A - Search Results

1

Performance and data interpretation of the in vivo comet assay in pharmaceutical industry: EFPIA survey results.

van der Leede BJ, Doherty A, Guérard M, Howe J, O'Donovan M, Plappert-Helbig U, Thybaud V. van der Leede BJ, et al. Among authors: doherty a. Mutat Res Genet Toxicol Environ Mutagen. 2014 Dec;775-776:81-8. doi: 10.1016/j.mrgentox.2014.09.008. Epub 2014 Oct 5. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25435358 Free article.

2

Anomalous genotoxic responses induced in mouse lymphoma L5178Y cells by potassium bromate.

Priestley CC, Green RM, Fellows MD, Doherty AT, Hodges NJ, O'Donovan MR. Priestley CC, et al. Toxicology. 2010 Jan 12;267(1-3):45-53. doi: 10.1016/j.tox.2009.10.012. Epub 2009 Oct 22. Toxicology. 2010. PMID: 19853637

3

A rapid, semi-automated method for scoring micronuclei in mononucleated mouse lymphoma cells.

Doherty AT, Hayes J, Fellows M, Kirk S, O'Donovan M. Doherty AT, et al. Mutat Res. 2011 Nov 27;726(1):36-41. doi: 10.1016/j.mrgentox.2011.08.002. Epub 2011 Aug 26. Mutat Res. 2011. PMID: 21889997

4

Chromosome aberration frequency in rat peripheral lymphocytes increases with repeated dosing with hexamethylphosphoramide or cyclophosphamide.

Doherty AT, Hayes J, Holme P, O'Donovan M. Doherty AT, et al. Mutagenesis. 2012 Sep;27(5):533-9. doi: 10.1093/mutage/ges016. Epub 2012 Apr 6. Mutagenesis. 2012. PMID: 22492203

5

Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. I: glucocorticoid receptor agonism.

Hayes JE, Doherty AT, Coulson M, Foster JR, Cotton PT, O'Donovan MR. Hayes JE, et al. Mutagenesis. 2013 Mar;28(2):227-32. doi: 10.1093/mutage/ges076. Epub 2013 Jan 21. Mutagenesis. 2013. PMID: 23340811

6

Where will genetic toxicology testing be in 30 years' time? Summary report of the 25th Industrial Genotoxicity Group Meeting, Royal Society of Medicine, London, November 9, 2011.

Ellis P, Fowler P, Booth E, Kidd D, Howe J, Doherty A, Scott A. Ellis P, et al. Among authors: doherty a. Mutagenesis. 2014 Jan;29(1):73-7. doi: 10.1093/mutage/get057. Epub 2013 Dec 11. Mutagenesis. 2014. PMID: 24334751

7

Genotoxins induce binucleation in L5178Y and TK6 cells.

Doherty AT, Wilson A, Chocian K, Molloy J, Clatworthy M, Doak S, Jenkins G, O'Donovan M. Doherty AT, et al. Mutat Res Genet Toxicol Environ Mutagen. 2014 Aug;770:29-34. doi: 10.1016/j.mrgentox.2014.05.005. Epub 2014 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25344161

8

Evaluation of 4,4'-diaminodiphenyl ether in the rat comet assay: Part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiative international validation study of in vivo rat alkaline comet assay.

Priestley CC, Walker JS, O'Donovan MR, Doherty AT. Priestley CC, et al. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:125-8. doi: 10.1016/j.mrgentox.2015.06.011. Epub 2015 Jun 18. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212302

9

The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.

Brüsehafer K, Manshian BB, Doherty AT, Zaïr ZM, Johnson GE, Doak SH, Jenkins GJ. Brüsehafer K, et al. Mutagenesis. 2016 Mar;31(2):171-80. doi: 10.1093/mutage/gev069. Epub 2015 Sep 11. Mutagenesis. 2016. PMID: 26362870 Free PMC article.

10

High information content assays for genetic toxicology testing: A report of the International Workshops on Genotoxicity Testing (IWGT).

Dertinger SD, Totsuka Y, Bielas JH, Doherty AT, Kleinjans J, Honma M, Marchetti F, Schuler MJ, Thybaud V, White P, Yauk CL. Dertinger SD, et al. Mutat Res Genet Toxicol Environ Mutagen. 2019 Nov;847:403022. doi: 10.1016/j.mrgentox.2019.02.003. Epub 2019 Feb 21. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31699343

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