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Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
Rothfuss A, O'Donovan M, De Boeck M, Brault D, Czich A, Custer L, Hamada S, Plappert-Helbig U, Hayashi M, Howe J, Kraynak AR, van der Leede BJ, Nakajima M, Priestley C, Thybaud V, Saigo K, Sawant S, Shi J, Storer R, Struwe M, Vock E, Galloway S. Rothfuss A, et al. Among authors: van der leede bj. Mutat Res. 2010 Sep 30;702(1):40-69. doi: 10.1016/j.mrgentox.2010.07.006. Epub 2010 Jul 23. Mutat Res. 2010. PMID: 20656055
Evaluation of p-phenylenediamine, o-phenylphenol sodium salt, and 2,4-diaminotoluene in the rat comet assay as part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiated international validation study of in vivo rat alkaline comet assay.
De Boeck M, van der Leede BJ, De Vlieger K, Geys H, Vynckier A, Van Gompel J. De Boeck M, et al. Among authors: van der leede bj. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:151-7. doi: 10.1016/j.mrgentox.2015.04.002. Epub 2015 Apr 7. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212306
A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.
Kirkland D, Whitwell J, Smith R, Hashimoto K, Ji Z, Kenny J, Koyama N, Lovell DP, Martus HJ, Meurer K, Roberts D, Takeiri A, Uno Y, van der Leede BJ, White P, Zeller A. Kirkland D, et al. Among authors: van der leede bj. Mutat Res Genet Toxicol Environ Mutagen. 2022 Jul-Aug;879-880:503503. doi: 10.1016/j.mrgentox.2022.503503. Epub 2022 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2022. PMID: 35914859 Free article.
Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and risk/benefit to patients.
Lachau-Durand S, Lammens L, van der Leede BJ, Van Gompel J, Bailey G, Engelen M, Lampo A. Lachau-Durand S, et al. Among authors: van der leede bj. PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0007026. doi: 10.1371/journal.pntd.0007026. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30650076 Free PMC article.
Optimisation of the cell cultivation methods in the embryonic stem cell test results in an increased differentiation potential of the cells into strong beating myocard cells.
De Smedt A, Steemans M, De Boeck M, Peters AK, van der Leede BJ, Van Goethem F, Lampo A, Vanparys P. De Smedt A, et al. Among authors: van goethem f, van der leede bj. Toxicol In Vitro. 2008 Oct;22(7):1789-96. doi: 10.1016/j.tiv.2008.07.003. Epub 2008 Jul 11. Toxicol In Vitro. 2008. PMID: 18672049
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity.
Van Heusden J, Van Ginckel R, Bruwiere H, Moelans P, Janssen B, Floren W, van der Leede BJ, van Dun J, Sanz G, Venet M, Dillen L, Van Hove C, Willemsens G, Janicot M, Wouters W. Van Heusden J, et al. Among authors: van dun j, van hove c, van ginckel r, van der leede bj. Br J Cancer. 2002 Feb 12;86(4):605-11. doi: 10.1038/sj.bjc.6600056. Br J Cancer. 2002. PMID: 11870544 Free PMC article.
24 results