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Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.
Focke-Tejkl M, Weber M, Niespodziana K, Neubauer A, Huber H, Henning R, Stegfellner G, Maderegger B, Hauer M, Stolz F, Niederberger V, Marth K, Eckl-Dorna J, Weiss R, Thalhamer J, Blatt K, Valent P, Valenta R. Focke-Tejkl M, et al. Among authors: neubauer a. J Allergy Clin Immunol. 2015 May;135(5):1207-7.e1-11. doi: 10.1016/j.jaci.2014.09.012. Epub 2014 Nov 13. J Allergy Clin Immunol. 2015. PMID: 25441634 Free PMC article.
Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32.
Niederberger V, Neubauer A, Gevaert P, Zidarn M, Worm M, Aberer W, Malling HJ, Pfaar O, Klimek L, Pfützner W, Ring J, Darsow U, Novak N, Gerth van Wijk R, Eckl-Dorna J, Focke-Tejkl M, Weber M, Müller HH, Klinger J, Stolz F, Breit N, Henning R, Valenta R. Niederberger V, et al. Among authors: neubauer a. J Allergy Clin Immunol. 2018 Aug;142(2):497-509.e9. doi: 10.1016/j.jaci.2017.09.052. Epub 2018 Jan 17. J Allergy Clin Immunol. 2018. PMID: 29361332 Free PMC article. Clinical Trial.
Two years of treatment with the recombinant grass pollen allergy vaccine BM32 induces a continuously increasing allergen-specific IgG4 response.
Eckl-Dorna J, Weber M, Stanek V, Linhart B, Ristl R, Waltl EE, Villazala-Merino S, Hummel A, Focke-Tejkl M, Froeschel R, Neubauer A, Henning R, Perkmann T, Valenta R, Niederberger V. Eckl-Dorna J, et al. Among authors: neubauer a. EBioMedicine. 2019 Dec;50:421-432. doi: 10.1016/j.ebiom.2019.11.006. Epub 2019 Nov 28. EBioMedicine. 2019. PMID: 31786130 Free PMC article.
Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly.
Campana R, Vrtala S, Maderegger B, Jertschin P, Stegfellner G, Swoboda I, Focke-Tejkl M, Blatt K, Gieras A, Zafred D, Neubauer A, Valent P, Keller W, Spitzauer S, Valenta R. Campana R, et al. Among authors: neubauer a. J Allergy Clin Immunol. 2010 Nov;126(5):1024-31, 1031.e1-8. doi: 10.1016/j.jaci.2010.05.023. Epub 2010 Jul 16. J Allergy Clin Immunol. 2010. PMID: 20638112
Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer.
Campana R, Vrtala S, Maderegger B, Dall'Antonia Y, Zafred D, Blatt K, Herrmann H, Focke-Tejkl M, Swoboda I, Scheiblhofer S, Gieras A, Neubauer A, Keller W, Valent P, Thalhamer J, Spitzauer S, Valenta R. Campana R, et al. Among authors: neubauer a. Mol Immunol. 2011 Jan;48(4):431-41. doi: 10.1016/j.molimm.2010.09.016. Epub 2010 Nov 18. Mol Immunol. 2011. PMID: 21093057 Free PMC article.
Recombinant allergens: what does the future hold?
Valenta R, Niespodziana K, Focke-Tejkl M, Marth K, Huber H, Neubauer A, Niederberger V. Valenta R, et al. Among authors: neubauer a. J Allergy Clin Immunol. 2011 Apr;127(4):860-4. doi: 10.1016/j.jaci.2011.02.016. J Allergy Clin Immunol. 2011. PMID: 21458656 Review.
Skin test evaluation of a novel peptide carrier-based vaccine, BM32, in grass pollen-allergic patients.
Niederberger V, Marth K, Eckl-Dorna J, Focke-Tejkl M, Weber M, Hemmer W, Berger U, Neubauer A, Stolz F, Henning R, Valenta R. Niederberger V, et al. Among authors: neubauer a. J Allergy Clin Immunol. 2015 Oct;136(4):1101-3.e8. doi: 10.1016/j.jaci.2015.03.034. Epub 2015 Jun 3. J Allergy Clin Immunol. 2015. PMID: 26048664 Free PMC article. Clinical Trial. No abstract available.
Frequent occurrence of T cell-mediated late reactions revealed by atopy patch testing with hypoallergenic rBet v 1 fragments.
Campana R, Moritz K, Marth K, Neubauer A, Huber H, Henning R, Blatt K, Hoermann G, Brodie TM, Kaider A, Valent P, Sallusto F, Wöhrl S, Valenta R. Campana R, et al. Among authors: neubauer a. J Allergy Clin Immunol. 2016 Feb;137(2):601-609.e8. doi: 10.1016/j.jaci.2015.08.042. Epub 2015 Oct 28. J Allergy Clin Immunol. 2016. PMID: 26518092 Free PMC article.
862 results