Wermuth CG - Search Results

1

Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.

Marivet MC, Bourguignon JJ, Lugnier C, Mann A, Stoclet JC, Wermuth CG. Marivet MC, et al. Among authors: wermuth cg. J Med Chem. 1989 Jul;32(7):1450-7. doi: 10.1021/jm00127a009. J Med Chem. 1989. PMID: 2544722

2

3-aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities.

Wermuth CG, Schlewer G, Bourguignon JJ, Maghioros G, Bouchet MJ, Moire C, Kan JP, Worms P, Biziere K. Wermuth CG, et al. J Med Chem. 1989 Mar;32(3):528-37. doi: 10.1021/jm00123a004. J Med Chem. 1989. PMID: 2563772

3

Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies.

Bourguignon JJ, Schoenfelder A, Schmitt M, Wermuth CG, Hechler V, Charlier B, Maitre M. Bourguignon JJ, et al. Among authors: wermuth cg. J Med Chem. 1988 May;31(5):893-7. doi: 10.1021/jm00400a001. J Med Chem. 1988. PMID: 3361576

4

9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.

Bourguignon JJ, Désaubry L, Raboisson P, Wermuth CG, Lugnier C. Bourguignon JJ, et al. Among authors: wermuth cg. J Med Chem. 1997 Jun 6;40(12):1768-70. doi: 10.1021/jm960827x. J Med Chem. 1997. PMID: 9191951 No abstract available.

5

5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists.

Rival Y, Hoffmann R, Didier B, Rybaltchenko V, Bourguignon JJ, Wermuth CG. Rival Y, et al. Among authors: wermuth cg. J Med Chem. 1998 Jan 29;41(3):311-7. doi: 10.1021/jm9705418. J Med Chem. 1998. PMID: 9464362

6

Purification of cAMP-specific phosphodiesterase from rat heart by affinity chromatography on immobilized rolipram.

Fougier S, Némoz G, Prigent AF, Marivet M, Bourguignon JJ, Wermuth C, Pacheco H. Fougier S, et al. Biochem Biophys Res Commun. 1986 Jul 16;138(1):205-14. doi: 10.1016/0006-291x(86)90267-6. Biochem Biophys Res Commun. 1986. PMID: 3017316

7

Synthesis and beta-adrenergic blocking activity of a novel class of aromatic oxime ethers.

Leclerc G, Mann A, Wermuth CG, Bieth N, Schwartz J. Leclerc G, et al. Among authors: wermuth cg. J Med Chem. 1977 Dec;20(12):1657-62. doi: 10.1021/jm00222a023. J Med Chem. 1977. PMID: 22751

8

Synthesis and biochemical evaluation of baclofen analogues locked in the baclofen solid-state conformation.

Mann A, Boulanger T, Brandau B, Durant F, Evrard G, Heaulme M, Desaulles E, Wermuth CG. Mann A, et al. Among authors: wermuth cg. J Med Chem. 1991 Apr;34(4):1307-13. doi: 10.1021/jm00108a011. J Med Chem. 1991. PMID: 1849996

9

The active analog approach applied to the pharmacophore identification of benzodiazepine receptor ligands.

Tebib S, Bourguignon JJ, Wermuth CG. Tebib S, et al. Among authors: wermuth cg. J Comput Aided Mol Des. 1987 Jul;1(2):153-70. doi: 10.1007/BF01676959. J Comput Aided Mol Des. 1987. PMID: 2848099

10

Tissue and substrate specificity of inhibition by alkoxy-aryl-lactams of platelet and arterial smooth muscle cyclic nucleotide phosphodiesterases relationship to pharmacological activity.

Lugnier C, Stierlé A, Beretz A, Schoeffter P, Lebec A, Wermuth CG, Cazenave JP, Stoclet JC. Lugnier C, et al. Among authors: wermuth cg. Biochem Biophys Res Commun. 1983 Jun 29;113(3):954-9. doi: 10.1016/0006-291x(83)91091-4. Biochem Biophys Res Commun. 1983. PMID: 6307307

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