Molecular mechanism of anesthetic-induced depression of myocardial contraction.
Meng T, Bu W, Ren X, Chen X, Yu J, Eckenhoff RG, Gao WD.
Meng T, et al. Among authors: bu w.
FASEB J. 2016 Aug;30(8):2915-25. doi: 10.1096/fj.201600290RR. Epub 2016 May 11.
FASEB J. 2016.
PMID: 27170289
Free PMC article.
Thus, propofol and isoflurane decrease force development by directly depressing myofilament Ca(2+) responsiveness and have binding sites in key regions for contraction in both actin and myosin.-Meng, T., Bu, W., Ren, X., Chen, X., Yu, J., Eckenhoff, R. G., Gao, W …
Thus, propofol and isoflurane decrease force development by directly depressing myofilament Ca(2+) responsiveness and have binding sites in …