Tsai KC - Search Results

1

Oseltamivir hydroxamate and acyl sulfonamide derivatives as influenza neuraminidase inhibitors.

Hong BT, Chen CL, Fang JM, Tsai KC, Wang SY, Huang WI, Cheng YE, Wong CH. Hong BT, et al. Among authors: tsai kc. Bioorg Med Chem. 2014 Dec 1;22(23):6647-6654. doi: 10.1016/j.bmc.2014.10.005. Bioorg Med Chem. 2014. PMID: 25456388

2

Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.

Lu IL, Mahindroo N, Liang PH, Peng YH, Kuo CJ, Tsai KC, Hsieh HP, Chao YS, Wu SY. Lu IL, et al. Among authors: tsai kc. J Med Chem. 2006 Aug 24;49(17):5154-61. doi: 10.1021/jm060207o. J Med Chem. 2006. PMID: 16913704

3

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.

Shao YM, Yang WB, Peng HP, Hsu MF, Tsai KC, Kuo TH, Wang AH, Liang PH, Lin CH, Yang AS, Wong CH. Shao YM, et al. Among authors: tsai kc. Chembiochem. 2007 Sep 24;8(14):1654-7. doi: 10.1002/cbic.200700254. Chembiochem. 2007. PMID: 17722121 Free PMC article.

4

Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.

Shie JJ, Fang JM, Wang SY, Tsai KC, Cheng YS, Yang AS, Hsiao SC, Su CY, Wong CH. Shie JJ, et al. Among authors: tsai kc. J Am Chem Soc. 2007 Oct 3;129(39):11892-3. doi: 10.1021/ja073992i. Epub 2007 Sep 12. J Am Chem Soc. 2007. PMID: 17850083 No abstract available.

5

Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease.

Shao YM, Yang WB, Kuo TH, Tsai KC, Lin CH, Yang AS, Liang PH, Wong CH. Shao YM, et al. Among authors: tsai kc. Bioorg Med Chem. 2008 Apr 15;16(8):4652-60. doi: 10.1016/j.bmc.2008.02.040. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18329272 Free PMC article.

6

The effect of different electrostatic potentials on docking accuracy: a case study using DOCK5.4.

Tsai KC, Wang SH, Hsiao NW, Li M, Wang B. Tsai KC, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3509-12. doi: 10.1016/j.bmcl.2008.05.026. Epub 2008 May 10. Bioorg Med Chem Lett. 2008. PMID: 18502122

7

The first pharmacophore model for potent NF-kappaB inhibitors.

Tsai KC, Teng LW, Shao YM, Chen YC, Lee YC, Li M, Hsiao NW. Tsai KC, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5665-9. doi: 10.1016/j.bmcl.2009.08.021. Epub 2009 Aug 8. Bioorg Med Chem Lett. 2009. PMID: 19726185

8

A comparison of different electrostatic potentials on prediction accuracy in CoMFA and CoMSIA studies.

Tsai KC, Chen YC, Hsiao NW, Wang CL, Lin CL, Lee YC, Li M, Wang B. Tsai KC, et al. Eur J Med Chem. 2010 Apr;45(4):1544-51. doi: 10.1016/j.ejmech.2009.12.063. Epub 2010 Jan 13. Eur J Med Chem. 2010. PMID: 20110138

9

Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses.

Wen WH, Wang SY, Tsai KC, Cheng YS, Yang AS, Fang JM, Wong CH. Wen WH, et al. Among authors: tsai kc. Bioorg Med Chem. 2010 Jun 1;18(11):4074-84. doi: 10.1016/j.bmc.2010.04.010. Epub 2010 Apr 8. Bioorg Med Chem. 2010. PMID: 20452227

10

A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity.

Shie JJ, Fang JM, Lai PT, Wen WH, Wang SY, Cheng YS, Tsai KC, Yang AS, Wong CH. Shie JJ, et al. Among authors: tsai kc. J Am Chem Soc. 2011 Nov 9;133(44):17959-65. doi: 10.1021/ja207892q. Epub 2011 Oct 14. J Am Chem Soc. 2011. PMID: 21942552

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