Jiang H - Search Results

1

A validated LC-MS/MS method for the simultaneous determination of BMS-791325, a hepatitis C virus NS5B RNA polymerase inhibitor, and its metabolite in plasma.

Yuan L, Jiang H, Zheng N, Xia YQ, Ouyang Z, Zeng J, Akinsanya B, Valentine JL, Moehlenkamp JD, Deng Y, Aubry AF, Arnold ME. Yuan L, et al. Among authors: jiang h. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 15;973C:1-8. doi: 10.1016/j.jchromb.2014.10.005. Epub 2014 Oct 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 25464088

2

A rugged and accurate liquid chromatography-tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma.

Jiang H, Zeng J, Deng Y, Xia YQ, Ouyang Z, Jemal M, Salcedo TW, Arnold ME. Jiang H, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2064-72. doi: 10.1016/j.jchromb.2011.05.036. Epub 2011 May 30. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21704571

3

A sensitive and accurate liquid chromatography-tandem mass spectrometry method for quantitative determination of the novel hepatitis C NS5A inhibitor BMS-790052 (daclastasvir) in human plasma and urine.

Jiang H, Zeng J, Kandoussi H, Liu Y, Wang X, Bifano M, Cojocaru L, Ryan J, Arnold ME. Jiang H, et al. J Chromatogr A. 2012 Jul 6;1245:117-21. doi: 10.1016/j.chroma.2012.05.028. Epub 2012 May 14. J Chromatogr A. 2012. PMID: 22640838

4

A rugged and accurate liquid chromatography-tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma.

Yuan L, Jiang H, Ouyang Z, Xia YQ, Zeng J, Peng Q, Lange RW, Deng Y, Arnold ME, Aubry AF. Yuan L, et al. Among authors: jiang h. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15;921-922:81-6. doi: 10.1016/j.jchromb.2013.01.029. Epub 2013 Feb 4. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23435345

5

Fully validated LC-MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serum.

Jiang H, Zeng J, Titsch C, Voronin K, Akinsanya B, Luo L, Shen H, Desai DD, Allentoff A, Aubry AF, Desilva BS, Arnold ME. Jiang H, et al. Anal Chem. 2013 Oct 15;85(20):9859-67. doi: 10.1021/ac402420v. Epub 2013 Sep 26. Anal Chem. 2013. PMID: 24024648

6

A user-friendly robotic sample preparation program for fully automated biological sample pipetting and dilution to benefit the regulated bioanalysis.

Jiang H, Ouyang Z, Zeng J, Yuan L, Zheng N, Jemal M, Arnold ME. Jiang H, et al. J Lab Autom. 2012 Jun;17(3):211-21. doi: 10.1177/2211068211429775. Epub 2012 Jan 24. J Lab Autom. 2012. PMID: 22357562

7

Calculation and mitigation of isotopic interferences in liquid chromatography-mass spectrometry/mass spectrometry assays and its application in supporting microdose absolute bioavailability studies.

Gu H, Wang J, Aubry AF, Jiang H, Zeng J, Easter J, Wang JS, Dockens R, Bifano M, Burrell R, Arnold ME. Gu H, et al. Among authors: jiang h. Anal Chem. 2012 Jun 5;84(11):4844-50. doi: 10.1021/ac300442v. Epub 2012 May 10. Anal Chem. 2012. PMID: 22540405

8

Practical and efficient strategy for evaluating oral absolute bioavailability with an intravenous microdose of a stable isotopically-labeled drug using a selected reaction monitoring mass spectrometry assay.

Jiang H, Zeng J, Li W, Bifano M, Gu H, Titsch C, Easter J, Burrell R, Kandoussi H, Aubry AF, Arnold ME. Jiang H, et al. Anal Chem. 2012 Nov 20;84(22):10031-7. doi: 10.1021/ac3024558. Epub 2012 Nov 6. Anal Chem. 2012. PMID: 23106420

9

Innovative use of LC-MS/MS for simultaneous quantitation of neutralizing antibody, residual drug, and human immunoglobulin G in immunogenicity assay development.

Jiang H, Xu W, Titsch CA, Furlong MT, Dodge R, Voronin K, Allentoff A, Zeng J, Aubry AF, DeSilva BS, Arnold ME. Jiang H, et al. Anal Chem. 2014 Mar 4;86(5):2673-80. doi: 10.1021/ac5001465. Epub 2014 Feb 17. Anal Chem. 2014. PMID: 24506335

10

Development and validation of an LC-MS/MS assay for the quantitation of a PEGylated anti-CD28 domain antibody in human serum: overcoming interference from antidrug antibodies and soluble target.

Gong C, Zeng J, Akinsanya B, Jiang H, Mora J, Chilewski S, Gambardella J, Allentoff A, Gleason C, Aubry AF, DeSilva BS, Arnold ME. Gong C, et al. Among authors: jiang h. Bioanalysis. 2014 Sep;6(18):2371-83. doi: 10.4155/bio.14.181. Bioanalysis. 2014. PMID: 25384590

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