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STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade.
Varikuti S, Oghumu S, Elbaz M, Volpedo G, Ahirwar DK, Alarcon PC, Sperling RH, Moretti E, Pioso MS, Kimble J, Nasser MW, Ganju RK, Terrazas C, Satoskar AR. Varikuti S, et al. Among authors: kimble j. Oncoimmunology. 2017 Aug 14;6(11):e1361088. doi: 10.1080/2162402X.2017.1361088. eCollection 2017. Oncoimmunology. 2017. PMID: 29147627 Free PMC article.
A higher order PUF complex is central to regulation of C. elegans germline stem cells.
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ, Kimble J, Hall TMT. Qiu C, et al. Among authors: kimble j. Nat Commun. 2025 Jan 2;16(1):123. doi: 10.1038/s41467-024-55526-x. Nat Commun. 2025. PMID: 39747099 Free PMC article.
Mutation of GLP-1/Notch RAM domain results in a strong Glp-1 phenotype.
Crittenden SL, Dos Santos SJC, Battula S, Kimble J. Crittenden SL, et al. Among authors: kimble j. MicroPubl Biol. 2024 Nov 7;2024:10.17912/micropub.biology.001391. doi: 10.17912/micropub.biology.001391. eCollection 2024. MicroPubl Biol. 2024. PMID: 39583580 Free PMC article.
263 results