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Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.
Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, Goldszmid R, McVicar DW, Lyakh L, Trinchieri G. Cardone M, et al. Among authors: steinhagen f. PLoS One. 2014 Dec 4;9(12):e114516. doi: 10.1371/journal.pone.0114516. eCollection 2014. PLoS One. 2014. PMID: 25474109 Free PMC article.
Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation.
Stewart CA, Metheny H, Iida N, Smith L, Hanson M, Steinhagen F, Leighty RM, Roers A, Karp CL, Müller W, Trinchieri G. Stewart CA, et al. Among authors: steinhagen f. J Clin Invest. 2013 Nov;123(11):4859-74. doi: 10.1172/JCI65180. J Clin Invest. 2013. PMID: 24216477 Free PMC article.
β-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-α production by human plasmacytoid dendritic cells, and promote inflammation.
Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, Howard OM, Shirota H, Steinhagen F, Klinman DM, Yang D, Oppenheim JJ. Tewary P, et al. Among authors: steinhagen f. J Immunol. 2013 Jul 15;191(2):865-74. doi: 10.4049/jimmunol.1201648. Epub 2013 Jun 17. J Immunol. 2013. PMID: 23776172 Free PMC article.
CpG DNA as a vaccine adjuvant.
Bode C, Zhao G, Steinhagen F, Kinjo T, Klinman DM. Bode C, et al. Among authors: steinhagen f. Expert Rev Vaccines. 2011 Apr;10(4):499-511. doi: 10.1586/erv.10.174. Expert Rev Vaccines. 2011. PMID: 21506647 Free PMC article. Review.
TLR-based immune adjuvants.
Steinhagen F, Kinjo T, Bode C, Klinman DM. Steinhagen F, et al. Vaccine. 2011 Apr 12;29(17):3341-55. doi: 10.1016/j.vaccine.2010.08.002. Epub 2010 Aug 14. Vaccine. 2011. PMID: 20713100 Free PMC article. Review.
31 results