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Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.
Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY. Gibson CC, et al. Among authors: thomas kr. Circulation. 2015 Jan 20;131(3):289-99. doi: 10.1161/CIRCULATIONAHA.114.010403. Epub 2014 Dec 8. Circulation. 2015. PMID: 25486933 Free PMC article.
Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium.
Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY. Gibson CC, et al. Among authors: thomas kr. PLoS One. 2015 Oct 15;10(10):e0140370. doi: 10.1371/journal.pone.0140370. eCollection 2015. PLoS One. 2015. PMID: 26469335 Free PMC article.
Netrin-4 activates endothelial integrin {alpha}6{beta}1.
Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY. Larrieu-Lahargue F, et al. Among authors: thomas kr. Circ Res. 2011 Sep 16;109(7):770-4. doi: 10.1161/CIRCRESAHA.111.247239. Epub 2011 Jul 28. Circ Res. 2011. PMID: 21799154 Free PMC article.
Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.
Zhu W, Shi DS, Winter JM, Rich BE, Tong Z, Sorensen LK, Zhao H, Huang Y, Tai Z, Mleynek TM, Yoo JH, Dunn C, Ling J, Bergquist JA, Richards JR, Jiang A, Lesniewski LA, Hartnett ME, Ward DM, Mueller AL, Ostanin K, Thomas KR, Odelberg SJ, Li DY. Zhu W, et al. Among authors: thomas kr. J Clin Invest. 2017 Dec 1;127(12):4569-4582. doi: 10.1172/JCI91770. Epub 2017 Oct 23. J Clin Invest. 2017. PMID: 29058688 Free PMC article.
Netrin ligands and receptors: lessons from neurons to the endothelium.
Larrieu-Lahargue F, Thomas KR, Li DY. Larrieu-Lahargue F, et al. Among authors: thomas kr. Trends Cardiovasc Med. 2012 Feb;22(2):44-7. doi: 10.1016/j.tcm.2012.06.010. Epub 2012 Jul 28. Trends Cardiovasc Med. 2012. PMID: 22841834 Free PMC article. Review.
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, Li DY. Jones CA, et al. Among authors: thomas kr. Nat Cell Biol. 2009 Nov;11(11):1325-31. doi: 10.1038/ncb1976. Epub 2009 Oct 18. Nat Cell Biol. 2009. PMID: 19855388 Free PMC article.
Netrin-4 induces lymphangiogenesis in vivo.
Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY. Larrieu-Lahargue F, et al. Among authors: thomas kr. Blood. 2010 Jul 1;115(26):5418-26. doi: 10.1182/blood-2009-11-252338. Epub 2010 Apr 20. Blood. 2010. PMID: 20407033 Free PMC article.
ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.
Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY. Yoo JH, et al. Among authors: thomas kr. Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2. Cancer Cell. 2016. PMID: 27265506 Free PMC article.
The netrin receptor UNC5B promotes angiogenesis in specific vascular beds.
Navankasattusas S, Whitehead KJ, Suli A, Sorensen LK, Lim AH, Zhao J, Park KW, Wythe JD, Thomas KR, Chien CB, Li DY. Navankasattusas S, et al. Among authors: thomas kr. Development. 2008 Feb;135(4):659-67. doi: 10.1242/dev.013623. Development. 2008. PMID: 18223200 Free PMC article.
222 results