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Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.
Colbeck EJ, Hindley JP, Smart K, Jones E, Bloom A, Bridgeman H, McPherson RC, Turner DG, Ladell K, Price DA, O'Connor RA, Anderton SM, Godkin AJ, Gallimore AM. Colbeck EJ, et al. Among authors: hindley jp. Oncotarget. 2015 Sep 22;6(28):24649-59. doi: 10.18632/oncotarget.5584. Oncotarget. 2015. PMID: 26433463 Free PMC article.
Treg Depletion Licenses T Cell-Driven HEV Neogenesis and Promotes Tumor Destruction.
Colbeck EJ, Jones E, Hindley JP, Smart K, Schulz R, Browne M, Cutting S, Williams A, Parry L, Godkin A, Ware CF, Ager A, Gallimore A. Colbeck EJ, et al. Among authors: hindley jp. Cancer Immunol Res. 2017 Nov;5(11):1005-1015. doi: 10.1158/2326-6066.CIR-17-0131. Epub 2017 Sep 25. Cancer Immunol Res. 2017. PMID: 28947544 Free PMC article.
Immune Remodeling of the Extracellular Matrix Drives Loss of Cancer Stem Cells and Tumor Rejection.
Pires A, Greenshields-Watson A, Jones E, Smart K, Lauder SN, Somerville M, Milutinovic S, Kendrick H, Hindley JP, French R, Smalley MJ, Watkins WJ, Andrews R, Godkin A, Gallimore A. Pires A, et al. Among authors: hindley jp. Cancer Immunol Res. 2020 Dec;8(12):1520-1531. doi: 10.1158/2326-6066.CIR-20-0070. Epub 2020 Oct 6. Cancer Immunol Res. 2020. PMID: 33023965 Free PMC article.
Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cells via blood vessels and lymphatics.
Ondondo B, Jones E, Hindley J, Cutting S, Smart K, Bridgeman H, Matthews KK, Ladell K, Price DA, Jackson DG, Godkin A, Ager A, Gallimore A. Ondondo B, et al. Among authors: hindley j. Int J Cancer. 2014 May 1;134(9):2156-67. doi: 10.1002/ijc.28556. Epub 2013 Nov 8. Int J Cancer. 2014. PMID: 24142504 Free PMC article.
117 results