Wong N - Search Results

1

Loss of the Notch effector RBPJ promotes tumorigenesis.

Kulic I, Robertson G, Chang L, Baker JH, Lockwood WW, Mok W, Fuller M, Fournier M, Wong N, Chou V, Robinson MD, Chun HJ, Gilks B, Kempkes B, Thomson TA, Hirst M, Minchinton AI, Lam WL, Jones S, Marra M, Karsan A. Kulic I, et al. Among authors: wong n. J Exp Med. 2015 Jan 12;212(1):37-52. doi: 10.1084/jem.20121192. Epub 2014 Dec 15. J Exp Med. 2015. PMID: 25512468 Free PMC article.

2

Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations.

Wong NK, Fuller M, Sung S, Wong F, Karsan A. Wong NK, et al. Cancer Med. 2012 Oct;1(2):105-13. doi: 10.1002/cam4.18. Epub 2012 Jul 18. Cancer Med. 2012. PMID: 23342261 Free PMC article.

3

Differential function of PTPalpha and PTPalpha Y789F in T cells and regulation of PTPalpha phosphorylation at Tyr-789 by CD45.

Maksumova L, Wang Y, Wong NK, Le HT, Pallen CJ, Johnson P. Maksumova L, et al. J Biol Chem. 2007 Jul 20;282(29):20925-32. doi: 10.1074/jbc.M703157200. Epub 2007 May 16. J Biol Chem. 2007. PMID: 17507376 Free article.

4

CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.

Wong NK, Lai JC, Birkenhead D, Shaw AS, Johnson P. Wong NK, et al. J Immunol. 2008 Nov 15;181(10):7033-43. doi: 10.4049/jimmunol.181.10.7033. J Immunol. 2008. PMID: 18981123

5

NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition.

Llaurado Fernandez M, Hijmans EM, Gennissen AMC, Wong NKY, Li S, Wisman GBA, Hamilton A, Hoenisch J, Dawson A, Lee CH, Bittner M, Kim H, DiMattia GE, Lok CAR, Lieftink C, Beijersbergen RL, de Jong S, Carey MS, Bernards R, Berns K. Llaurado Fernandez M, et al. Mol Cancer Ther. 2022 Dec 2;21(12):1862-1874. doi: 10.1158/1535-7163.MCT-22-0004. Mol Cancer Ther. 2022. PMID: 36198031 Free PMC article.

6

CD44-mediated elongated T cell spreading requires Pyk2 activation by Src family kinases, extracellular calcium, phospholipase C and phosphatidylinositol-3 kinase.

Wong NK, Lai JC, Maeshima N, Johnson P. Wong NK, et al. Cell Signal. 2011 May;23(5):812-9. doi: 10.1016/j.cellsig.2011.01.003. Epub 2011 Jan 14. Cell Signal. 2011. PMID: 21238585

7

Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic Vulnerability.

Shrestha R, Llaurado Fernandez M, Dawson A, Hoenisch J, Volik S, Lin YY, Anderson S, Kim H, Haegert AM, Colborne S, Wong NKY, McConeghy B, Bell RH, Brahmbhatt S, Lee CH, DiMattia GE, Le Bihan S, Morin GB, Collins CC, Carey MS. Shrestha R, et al. Cancer Res. 2021 Apr 1;81(7):1681-1694. doi: 10.1158/0008-5472.CAN-20-2222. Epub 2021 Jan 13. Cancer Res. 2021. PMID: 33441310

8

Modeling Androgen Deprivation Therapy-Induced Prostate Cancer Dormancy and Its Clinical Implications.

Dong X, Xue H, Mo F, Lin YY, Lin D, Wong NKY, Sun Y, Wilkinson S, Ku AT, Hao J, Ci X, Wu R, Haegert A, Silver R, Taplin ME, Balk SP, Alumkal JJ, Sowalsky AG, Gleave M, Collins C, Wang Y. Dong X, et al. Mol Cancer Res. 2022 May 4;20(5):782-793. doi: 10.1158/1541-7786.MCR-21-1037. Mol Cancer Res. 2022. PMID: 35082166 Free PMC article.

9

Framework of Intrinsic Immune Landscape of Dormant Prostate Cancer.

Wong NKY, Dong X, Lin YY, Xue H, Wu R, Lin D, Collins C, Wang Y. Wong NKY, et al. Cells. 2022 May 5;11(9):1550. doi: 10.3390/cells11091550. Cells. 2022. PMID: 35563856 Free PMC article.

10

CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.

Li R, Wong N, Jabali MD, Johnson P. Li R, et al. Among authors: wong n. J Biol Chem. 2001 Aug 3;276(31):28767-73. doi: 10.1074/jbc.M100158200. Epub 2001 May 21. J Biol Chem. 2001. PMID: 11369760 Free article.

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