Bylund J - Search Results

1

Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues.

Fransson R, Nordvall G, Bylund J, Carlsson-Jonsson A, Kratz JM, Svensson R, Artursson P, Hallberg M, Sandström A. Fransson R, et al. Among authors: bylund j. ACS Med Chem Lett. 2014 Oct 29;5(12):1272-7. doi: 10.1021/ml5002954. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516784 Free PMC article.

2

Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship.

Macsari I, Sandberg L, Besidski Y, Gravenfors Y, Ginman T, Bylund J, Bueters T, Eriksson AB, Lund PE, Venyike E, Arvidsson PI. Macsari I, et al. Among authors: bylund j. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3871-6. doi: 10.1016/j.bmcl.2011.05.041. Epub 2011 May 18. Bioorg Med Chem Lett. 2011. PMID: 21641215

3

Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.

Besidski Y, Brown W, Bylund J, Dabrowski M, Dautrey S, Harter M, Horoszok L, Hu Y, Johnson D, Johnstone S, Jones P, Leclerc S, Kolmodin K, Kers I, Labarre M, Labrecque D, Laird J, Lundström T, Martino J, Maudet M, Munro A, Nylöf M, Penwell A, Rotticci D, Slaitas A, Sundgren-Andersson A, Svensson M, Terp G, Villanueva H, Walpole C, Zemribo R, Griffin AM. Besidski Y, et al. Among authors: bylund j. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6205-11. doi: 10.1016/j.bmcl.2012.08.018. Epub 2012 Aug 14. Bioorg Med Chem Lett. 2012. PMID: 22939234

4

Discovery of novel pyrrolopyridazine scaffolds as transient receptor potential vanilloid (TRPV1) antagonists.

Dorange I, Forsblom R, Macsari I, Svensson M, Bylund J, Besidski Y, Blid J, Sohn D, Gravenfors Y. Dorange I, et al. Among authors: bylund j. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6888-95. doi: 10.1016/j.bmcl.2012.09.059. Epub 2012 Sep 25. Bioorg Med Chem Lett. 2012. PMID: 23058884

5

Amide hydrolysis of a novel chemical series of microsomal prostaglandin E synthase-1 inhibitors induces kidney toxicity in the rat.

Bylund J, Annas A, Hellgren D, Bjurström S, Andersson H, Svanhagen A. Bylund J, et al. Drug Metab Dispos. 2013 Mar;41(3):634-41. doi: 10.1124/dmd.112.048983. Epub 2013 Jan 2. Drug Metab Dispos. 2013. PMID: 23284082

6

Stepwise Design of γ-Secretase Modulators with an Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring Bioisostere.

Rodríguez Sarmiento RM, Bissantz C, Bylund J, Limberg A, Neidhart W, Jakob-Roetne R, Wang L, Baumann K. Rodríguez Sarmiento RM, et al. Among authors: bylund j. J Med Chem. 2020 Aug 13;63(15):8534-8553. doi: 10.1021/acs.jmedchem.0c00909. Epub 2020 Aug 4. J Med Chem. 2020. PMID: 32706964

7

Metabolic profiling of TRPV1 antagonists of the benzothiazole amide series: implications for in vitro genotoxicity assessment.

Bylund J, Petersson C, Lindgren A, Olofsson S, Czene S. Bylund J, et al. Xenobiotica. 2013 Feb;43(2):201-10. doi: 10.3109/00498254.2012.708459. Epub 2012 Aug 7. Xenobiotica. 2013. PMID: 22867274

8

The volume of distribution is an indicator of poor in vitro-in vivo extrapolation of clearance for acidic drugs in the rat.

Sohlenius-Sternbeck AK, Fagerholm U, Bylund J. Sohlenius-Sternbeck AK, et al. Among authors: bylund j. Xenobiotica. 2013 Aug;43(8):671-8. doi: 10.3109/00498254.2012.755578. Epub 2013 Jan 16. Xenobiotica. 2013. PMID: 23323549

9

Rat poorly predicts the combined non-absorbed and presystemically metabolized fractions in the human.

Bueters T, Juric S, Sohlenius-Sternbeck AK, Hu Y, Bylund J. Bueters T, et al. Among authors: bylund j. Xenobiotica. 2013 Jul;43(7):607-16. doi: 10.3109/00498254.2012.752117. Epub 2013 Jan 2. Xenobiotica. 2013. PMID: 23278250

10

Optimizing DMPK Properties: Experiences from a Big Pharma DMPK Department.

Sohlenius-Sternbeck AK, Janson J, Bylund J, Baranczewski P, Breitholtz-Emanuelsson A, Hu Y, Tsoi C, Lindgren A, Gissberg O, Bueters T, Briem S, Juric S, Johansson J, Bergh M, Hoogstraate J. Sohlenius-Sternbeck AK, et al. Among authors: bylund j. Curr Drug Metab. 2016;17(3):253-70. doi: 10.2174/1389200217666151210125637. Curr Drug Metab. 2016. PMID: 26651977 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

189 results

Search Page

Filters