Van Rooyen DM - Search Results

1

Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.

Ioannou GN, Van Rooyen DM, Savard C, Haigh WG, Yeh MM, Teoh NC, Farrell GC. Ioannou GN, et al. Among authors: van rooyen dm. J Lipid Res. 2015 Feb;56(2):277-85. doi: 10.1194/jlr.M053785. Epub 2014 Dec 17. J Lipid Res. 2015. PMID: 25520429 Free PMC article.

2

Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis.

Van Rooyen DM, Larter CZ, Haigh WG, Yeh MM, Ioannou G, Kuver R, Lee SP, Teoh NC, Farrell GC. Van Rooyen DM, et al. Gastroenterology. 2011 Oct;141(4):1393-403, 1403.e1-5. doi: 10.1053/j.gastro.2011.06.040. Epub 2011 Jun 23. Gastroenterology. 2011. PMID: 21703998 Free PMC article.

3

Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome.

Van Rooyen DM, Gan LT, Yeh MM, Haigh WG, Larter CZ, Ioannou G, Teoh NC, Farrell GC. Van Rooyen DM, et al. J Hepatol. 2013 Jul;59(1):144-52. doi: 10.1016/j.jhep.2013.02.024. Epub 2013 Mar 7. J Hepatol. 2013. PMID: 23500152

4

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.

Mridha AR, Wree A, Robertson AAB, Yeh MM, Johnson CD, Van Rooyen DM, Haczeyni F, Teoh NC, Savard C, Ioannou GN, Masters SL, Schroder K, Cooper MA, Feldstein AE, Farrell GC. Mridha AR, et al. Among authors: van rooyen dm. J Hepatol. 2017 May;66(5):1037-1046. doi: 10.1016/j.jhep.2017.01.022. Epub 2017 Feb 3. J Hepatol. 2017. PMID: 28167322 Free PMC article.

5

NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications.

Farrell GC, van Rooyen D, Gan L, Chitturi S. Farrell GC, et al. Gut Liver. 2012 Apr;6(2):149-71. doi: 10.5009/gnl.2012.6.2.149. Epub 2012 Apr 17. Gut Liver. 2012. PMID: 22570745 Free PMC article.

6

Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice.

Larter CZ, Yeh MM, Van Rooyen DM, Teoh NC, Brooling J, Hou JY, Williams J, Clyne M, Nolan CJ, Farrell GC. Larter CZ, et al. Among authors: van rooyen dm. J Gastroenterol Hepatol. 2009 Oct;24(10):1658-68. doi: 10.1111/j.1440-1746.2009.05996.x. J Gastroenterol Hepatol. 2009. PMID: 19788606

7

Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis.

Larter CZ, Yeh MM, Van Rooyen DM, Brooling J, Ghatora K, Farrell GC. Larter CZ, et al. Among authors: van rooyen dm. J Gastroenterol Hepatol. 2012 Feb;27(2):341-50. doi: 10.1111/j.1440-1746.2011.06939.x. J Gastroenterol Hepatol. 2012. PMID: 21929649

8

Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease.

Larter CZ, Yeh MM, Haigh WG, Van Rooyen DM, Brooling J, Heydet D, Nolan CJ, Teoh NC, Farrell GC. Larter CZ, et al. Among authors: van rooyen dm. Obesity (Silver Spring). 2013 Jun;21(6):1189-99. doi: 10.1002/oby.20123. Epub 2013 May 10. Obesity (Silver Spring). 2013. PMID: 23666886 Free article.

9

Strain dependence of diet-induced NASH and liver fibrosis in obese mice is linked to diabetes and inflammatory phenotype.

Farrell GC, Mridha AR, Yeh MM, Arsov T, Van Rooyen DM, Brooling J, Nguyen T, Heydet D, Delghingaro-Augusto V, Nolan CJ, Shackel NA, McLennan SV, Teoh NC, Larter CZ. Farrell GC, et al. Among authors: van rooyen dm. Liver Int. 2014 Aug;34(7):1084-93. doi: 10.1111/liv.12335. Epub 2013 Oct 25. Liver Int. 2014. PMID: 24107103

10

Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fed foz/foz mice.

Legry V, Van Rooyen DM, Lambert B, Sempoux C, Poekes L, Español-Suñer R, Molendi-Coste O, Horsmans Y, Farrell GC, Leclercq IA. Legry V, et al. Among authors: van rooyen dm. Clin Sci (Lond). 2014 Oct;127(7):507-18. doi: 10.1042/CS20140026. Clin Sci (Lond). 2014. PMID: 24766485

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