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RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
Daigle JG, Lanson NA Jr, Smith RB, Casci I, Maltare A, Monaghan J, Nichols CD, Kryndushkin D, Shewmaker F, Pandey UB. Daigle JG, et al. Among authors: pandey ub. Hum Mol Genet. 2013 Mar 15;22(6):1193-205. doi: 10.1093/hmg/dds526. Epub 2012 Dec 20. Hum Mol Genet. 2013. PMID: 23257289 Free PMC article.
A fruitful endeavor: modeling ALS in the fruit fly.
Casci I, Pandey UB. Casci I, et al. Among authors: pandey ub. Brain Res. 2015 May 14;1607:47-74. doi: 10.1016/j.brainres.2014.09.064. Epub 2014 Oct 5. Brain Res. 2015. PMID: 25289585 Free PMC article. Review.
Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy.
Scaramuzzino C, Casci I, Parodi S, Lievens PMJ, Polanco MJ, Milioto C, Chivet M, Monaghan J, Mishra A, Badders N, Aggarwal T, Grunseich C, Sambataro F, Basso M, Fackelmayer FO, Taylor JP, Pandey UB, Pennuto M. Scaramuzzino C, et al. Among authors: pandey ub. Neuron. 2015 Jan 7;85(1):88-100. doi: 10.1016/j.neuron.2014.12.031. Neuron. 2015. PMID: 25569348 Free PMC article.
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
Daigle JG, Krishnamurthy K, Ramesh N, Casci I, Monaghan J, McAvoy K, Godfrey EW, Daniel DC, Johnson EM, Monahan Z, Shewmaker F, Pasinelli P, Pandey UB. Daigle JG, et al. Among authors: pandey ub. Acta Neuropathol. 2016 Apr;131(4):605-20. doi: 10.1007/s00401-015-1530-0. Epub 2016 Jan 4. Acta Neuropathol. 2016. PMID: 26728149 Free PMC article.
RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration.
Bakthavachalu B, Huelsmeier J, Sudhakaran IP, Hillebrand J, Singh A, Petrauskas A, Thiagarajan D, Sankaranarayanan M, Mizoue L, Anderson EN, Pandey UB, Ross E, VijayRaghavan K, Parker R, Ramaswami M. Bakthavachalu B, et al. Among authors: pandey ub. Neuron. 2018 May 16;98(4):754-766.e4. doi: 10.1016/j.neuron.2018.04.032. Neuron. 2018. PMID: 29772202 Free article.
75 results