Wen X - Search Results

1

Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.

Wen X, Tan W, Westergard T, Krishnamurthy K, Markandaiah SS, Shi Y, Lin S, Shneider NA, Monaghan J, Pandey UB, Pasinelli P, Ichida JK, Trotti D. Wen X, et al. Neuron. 2014 Dec 17;84(6):1213-25. doi: 10.1016/j.neuron.2014.12.010. Neuron. 2014. PMID: 25521377 Free PMC article.

2

Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.

Wen X, Westergard T, Pasinelli P, Trotti D. Wen X, et al. Neurosci Lett. 2017 Jan 1;636:16-26. doi: 10.1016/j.neulet.2016.09.007. Epub 2016 Sep 13. Neurosci Lett. 2017. PMID: 27619540 Free PMC article. Review.

3

Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD.

Westergard T, Jensen BK, Wen X, Cai J, Kropf E, Iacovitti L, Pasinelli P, Trotti D. Westergard T, et al. Among authors: wen x. Cell Rep. 2016 Oct 11;17(3):645-652. doi: 10.1016/j.celrep.2016.09.032. Cell Rep. 2016. PMID: 27732842 Free PMC article.

4

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK. Shi Y, et al. Among authors: wen x. Nat Med. 2018 Mar;24(3):313-325. doi: 10.1038/nm.4490. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400714 Free PMC article.

5

Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress.

Westergard T, McAvoy K, Russell K, Wen X, Pang Y, Morris B, Pasinelli P, Trotti D, Haeusler A. Westergard T, et al. Among authors: wen x. EMBO Mol Med. 2019 Feb;11(2):e9423. doi: 10.15252/emmm.201809423. EMBO Mol Med. 2019. PMID: 30617154 Free PMC article.

6

Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.

Jensen BK, Schuldi MH, McAvoy K, Russell KA, Boehringer A, Curran BM, Krishnamurthy K, Wen X, Westergard T, Ma L, Haeusler AR, Edbauer D, Pasinelli P, Trotti D. Jensen BK, et al. Among authors: wen x. EMBO Mol Med. 2020 May 8;12(5):e10722. doi: 10.15252/emmm.201910722. Epub 2020 Apr 29. EMBO Mol Med. 2020. PMID: 32347002 Free PMC article.

7

A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes.

Verdone BM, Cicardi ME, Wen X, Sriramoji S, Russell K, Markandaiah SS, Jensen BK, Krishnamurthy K, Haeusler AR, Pasinelli P, Trotti D. Verdone BM, et al. Among authors: wen x. Sci Rep. 2022 Apr 4;12(1):5644. doi: 10.1038/s41598-022-09593-z. Sci Rep. 2022. PMID: 35379876 Free PMC article.

8

The NFATC2/Nrf2 cascade regulates spinal cord ischemia-reperfusion injury by controlling inflammation, apoptosis and oxidative stress.

Li K, Lu L, Yao X, Wu Z, Sun P, Wen X, Li X, Wang K, Yin X. Li K, et al. Among authors: wen x. Regen Ther. 2024 Dec 7;28:126-133. doi: 10.1016/j.reth.2024.11.014. eCollection 2025 Mar. Regen Ther. 2024. PMID: 39720703 Free PMC article.

9

Empowering women with fetal malpositions: enhancing childbirth experience and empowerment through educational interventions: a randomized controlled clinical trial.

Wang X, Wang X, Wan X, Wen X, Lv C, Zhai J. Wang X, et al. Among authors: wen x. BMC Pregnancy Childbirth. 2024 Dec 24;24(1):859. doi: 10.1186/s12884-024-07092-9. BMC Pregnancy Childbirth. 2024. PMID: 39719592 Free article. Clinical Trial.

10

Enhanced and directional fluorescence emission regulated by dual resonant surface modes.

Li S, Huang H, Wen X, Wang P, Lu Y. Li S, et al. Among authors: wen x. Opt Lett. 2025 Jan 1;50(1):213-216. doi: 10.1364/OL.543250. Opt Lett. 2025. PMID: 39718891

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