Chapman HA - Search Results

1

Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling.

Xu P, Bailey-Bucktrout S, Xi Y, Xu D, Du D, Zhang Q, Xiang W, Liu J, Melton A, Sheppard D, Chapman HA, Bluestone JA, Derynck R. Xu P, et al. Among authors: chapman ha. Mol Cell. 2014 Dec 18;56(6):723-37. doi: 10.1016/j.molcel.2014.11.027. Mol Cell. 2014. PMID: 25526531 Free PMC article.

2

TGF-β1 Signaling and Tissue Fibrosis.

Kim KK, Sheppard D, Chapman HA. Kim KK, et al. Among authors: chapman ha. Cold Spring Harb Perspect Biol. 2018 Apr 2;10(4):a022293. doi: 10.1101/cshperspect.a022293. Cold Spring Harb Perspect Biol. 2018. PMID: 28432134 Free PMC article. Review.

3

Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis.

Wei Y, Kim TJ, Peng DH, Duan D, Gibbons DL, Yamauchi M, Jackson JR, Le Saux CJ, Calhoun C, Peters J, Derynck R, Backes BJ, Chapman HA. Wei Y, et al. Among authors: chapman ha. J Clin Invest. 2017 Oct 2;127(10):3675-3688. doi: 10.1172/JCI94624. Epub 2017 Sep 5. J Clin Invest. 2017. PMID: 28872461 Free PMC article.

4

Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline.

Xi Y, Tan K, Brumwell AN, Chen SC, Kim YH, Kim TJ, Wei Y, Chapman HA. Xi Y, et al. Among authors: chapman ha. Am J Respir Cell Mol Biol. 2014 Jan;50(1):51-60. doi: 10.1165/rcmb.2013-0099OC. Am J Respir Cell Mol Biol. 2014. PMID: 23944988 Free PMC article.

5

Gli1⁺ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung.

Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. Cassandras M, et al. Nat Cell Biol. 2020 Nov;22(11):1295-1306. doi: 10.1038/s41556-020-00591-9. Epub 2020 Oct 12. Nat Cell Biol. 2020. PMID: 33046884 Free PMC article.

6

Axin pathway activity regulates in vivo pY654-β-catenin accumulation and pulmonary fibrosis.

Ulsamer A, Wei Y, Kim KK, Tan K, Wheeler S, Xi Y, Thies RS, Chapman HA. Ulsamer A, et al. Among authors: chapman ha. J Biol Chem. 2012 Feb 10;287(7):5164-72. doi: 10.1074/jbc.M111.322123. Epub 2011 Dec 27. J Biol Chem. 2012. PMID: 22203675 Free PMC article.

7

Persistent Pathology in Influenza-Infected Mouse Lungs.

Kanegai CM, Xi Y, Donne ML, Gotts JE, Driver IH, Amidzic G, Lechner AJ, Jones KD, Vaughan AE, Chapman HA, Rock JR. Kanegai CM, et al. Among authors: chapman ha. Am J Respir Cell Mol Biol. 2016 Oct;55(4):613-615. doi: 10.1165/rcmb.2015-0387LE. Am J Respir Cell Mol Biol. 2016. PMID: 27689795 Free PMC article. No abstract available.

8

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix.

Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. Kim KK, et al. Among authors: chapman ha. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13180-5. doi: 10.1073/pnas.0605669103. Epub 2006 Aug 21. Proc Natl Acad Sci U S A. 2006. PMID: 16924102 Free PMC article.

9

Identification of pY654-β-catenin as a critical co-factor in hypoxia-inducible factor-1α signaling and tumor responses to hypoxia.

Xi Y, Wei Y, Sennino B, Ulsamer A, Kwan I, Brumwell AN, Tan K, Aghi MK, McDonald DM, Jablons DM, Chapman HA. Xi Y, et al. Among authors: chapman ha. Oncogene. 2013 Oct 17;32(42):5048-57. doi: 10.1038/onc.2012.530. Epub 2012 Dec 17. Oncogene. 2013. PMID: 23246962 Free PMC article.

10

Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.

Xi Y, Kim T, Brumwell AN, Driver IH, Wei Y, Tan V, Jackson JR, Xu J, Lee DK, Gotts JE, Matthay MA, Shannon JM, Chapman HA, Vaughan AE. Xi Y, et al. Among authors: chapman ha. Nat Cell Biol. 2017 Aug;19(8):904-914. doi: 10.1038/ncb3580. Epub 2017 Jul 24. Nat Cell Biol. 2017. PMID: 28737769 Free PMC article.

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