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Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria.
Di Sante G, Pestell TG, Casimiro MC, Bisetto S, Powell MJ, Lisanti MP, Cordon-Cardo C, Castillo-Martin M, Bonal DM, Debattisti V, Chen K, Wang L, He X, McBurney MW, Pestell RG. Di Sante G, et al. Among authors: he x. Am J Pathol. 2015 Jan;185(1):266-79. doi: 10.1016/j.ajpath.2014.09.014. Am J Pathol. 2015. PMID: 25529796 Free PMC article.
SirT1 fails to affect p53-mediated biological functions.
Kamel C, Abrol M, Jardine K, He X, McBurney MW. Kamel C, et al. Among authors: he x. Aging Cell. 2006 Feb;5(1):81-8. doi: 10.1111/j.1474-9726.2006.00191.x. Aging Cell. 2006. PMID: 16441846 Free article.
Reversible modulation of SIRT1 activity in a mouse strain.
Clark-Knowles KV, He X, Jardine K, Coulombe J, Dewar-Darch D, Caron AZ, Gray DA, McBurney MW. Clark-Knowles KV, et al. Among authors: he x. PLoS One. 2017 Mar 8;12(3):e0173002. doi: 10.1371/journal.pone.0173002. eCollection 2017. PLoS One. 2017. PMID: 28273169 Free PMC article.
SirT1 regulates energy metabolism and response to caloric restriction in mice.
Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, Xuan J, Evans M, Harper ME, McBurney MW. Boily G, et al. PLoS One. 2008 Mar 12;3(3):e1759. doi: 10.1371/journal.pone.0001759. PLoS One. 2008. PMID: 18335035 Free PMC article.
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