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Page 1
Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response.
Flaherty DP, Miller JR, Garshott DM, Hedrick M, Gosalia P, Li Y, Milewski M, Sugarman E, Vasile S, Salaniwal S, Su Y, Smith LH, Chung TD, Pinkerton AB, Aubé J, Callaghan MU, Golden JE, Fribley AM, Kaufman RJ. Flaherty DP, et al. Among authors: milewski m. ACS Med Chem Lett. 2014 Oct 29;5(12):1278-1283. doi: 10.1021/ml5003234. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25530830 Free PMC article.
Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.
Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Roth GP, Smith LH, Chung TD, Hanson GR, Thomas JB, Caron MG, Barak LS, Pinkerton AB. Peddibhotla S, et al. Among authors: milewski m. ACS Med Chem Lett. 2013 Jul 20;4(9):846-851. doi: 10.1021/ml400176n. ACS Med Chem Lett. 2013. PMID: 24611085 Free PMC article.
Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.
Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth GP, Diwan J, Chung TD, Jortzik E, Rahlfs S, Becker K, Pinkerton AB, Bode L. Preuss J, et al. Among authors: milewski m. J Med Chem. 2012 Aug 23;55(16):7262-72. doi: 10.1021/jm300833h. Epub 2012 Aug 6. J Med Chem. 2012. PMID: 22813531 Free PMC article.
Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor.
Maloney PR, Khan P, Hedrick M, Gosalia P, Milewski M, Li L, Roth GP, Sergienko E, Suyama E, Sugarman E, Nguyen K, Mehta A, Vasile S, Su Y, Stonich D, Nguyen H, Zeng FY, Novo AM, Vicchiarelli M, Diwan J, Chung TD, Smith LH, Pinkerton AB. Maloney PR, et al. Among authors: milewski m. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6656-60. doi: 10.1016/j.bmcl.2012.08.105. Epub 2012 Sep 7. Bioorg Med Chem Lett. 2012. PMID: 23010269 Free PMC article.
Decoding randomly ordered DNA arrays.
Gunderson KL, Kruglyak S, Graige MS, Garcia F, Kermani BG, Zhao C, Che D, Dickinson T, Wickham E, Bierle J, Doucet D, Milewski M, Yang R, Siegmund C, Haas J, Zhou L, Oliphant A, Fan JB, Barnard S, Chee MS. Gunderson KL, et al. Among authors: milewski m. Genome Res. 2004 May;14(5):870-7. doi: 10.1101/gr.2255804. Epub 2004 Apr 12. Genome Res. 2004. PMID: 15078854 Free PMC article.
Which Osteochondritis Dissecans Lesions Will Heal Nonoperatively? An Application of Machine Learning to the ROCK Prospective Cohort.
Johnstone T, Espiritu J, Tompkins M, Milewski MD, Nissen C, Shea KG; ROCK Group:; Nelson B, Egger A, Anderson C, Lee Pace J, Polousky J, Ellemann J, Meenen N, Edmonds E, Ellis H, Fabricant P, Krych A, Myer G, Kocher M, Carrey J. Johnstone T, et al. Among authors: milewski md. Orthop J Sports Med. 2024 Dec 16;12(12):23259671241297145. doi: 10.1177/23259671241297145. eCollection 2024 Dec. Orthop J Sports Med. 2024. PMID: 39697601 Free PMC article.
Impact of diabetes on epicardial reperfusion and mortality in a contemporary STEMI population undergoing mechanical reperfusion: Insights from the ISACS STEMI COVID 19 registry.
De Luca G, Algowhary M, Uguz B, Oliveira DC, Ganyukov V, Zimbakov Z, Cercek M, Jensen LO, Loh PH, Calmac L, Roura I Ferrer G, Quadros A, Milewski M, D'Uccio FS, von Birgelen C, Versaci F, Berg JT, Casella G, Lung AWS, Kala P, Díez Gil JL, Carrillo X, Dirksen M, Becerra-Munoz VM, Lee MK, Juzar DA, Moura Joaquim R, Paladino R, Milicic D, Davlouros P, Bakraceski N, Zilio F, Donazzan L, Kraaijeveld A, Galasso G, Arpad L, Lucia M, Vincenzo G, Menichelli M, Scoccia A, Yamac AH, Mert KU, Rios XF, Kovarnik T, Kidawa M, Moreu J, Flavien V, Fabris E, Martínez-Luengas IL, Ojeda FB, Rodríguez-Sanchez R, Caiazzo G, Cirrincione G, Kao HL, Forés JS, Vignali L, Pereira H, Manzo S, Ordoñez S, Özkan AA, Scheller B, Lehtola H, Teles R, Mantis C, Antti Y, Silveira JAB, Zoni R, Bessonov I, Savonitto S, Kochiadakis G, Alexopulos D, Uribe CE, Kanakakis J, Faurie B, Gabrielli G, Gutierrez Barrios A, Bachini JP, Rocha A, Tam FC, Rodriguez A, Lukito AA, Bellemain-Appaix A, Pessah G, Cortese G, Parodi G, Burgadha MA, Kedhi E, Lamelas P, Suryapranata H, Nardin M, Verdoia M. De Luca G, et al. Among authors: milewski m. Nutr Metab Cardiovasc Dis. 2024 Oct 24:103763. doi: 10.1016/j.numecd.2024.09.031. Online ahead of print. Nutr Metab Cardiovasc Dis. 2024. PMID: 39638679
A Simple Clinical Predictive Model for Arthroscopic Mobility of Osteochondritis Dissecans Lesions of the Knee.
Milewski MD, Miller PE, Gossman EC, Coene RP, Tompkins MA, Anderson CN, Bauer K, Busch MT, Carey JL, Carsen S, Chambers HG, Coene RP, Edmonds EW, Ellermann J, Ellis HB Jr, Erickson J, Fabricant PD, Ganley TJ, Gossman EC, Green DW, Heyworth BE, Hoi Po Hui J, Kocher MS, Krych AJ, Latz K, Lyon RM, Mayer S, Milewski MD, Miller PE, Nelson BJ, Nepple JJ, Nguyen JC, Nissen CW, Lee Pace J, Paterno MV, Pennock AT, Perkins C, Polousky JD, Saluan P, Shea KG, Tompkins MA, Wall EJ, Weiss JM, Willimon C, Wilson P, Wright RW, Zbojniewicz A, Myer GD. Milewski MD, et al. Am J Sports Med. 2024 Dec;52(14):3543-3550. doi: 10.1177/03635465241296133. Epub 2024 Nov 25. Am J Sports Med. 2024. PMID: 39584729
249 results