Khoo US - Search Results

1

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

Gong C, Fujino K, Monteiro LJ, Gomes AR, Drost R, Davidson-Smith H, Takeda S, Khoo US, Jonkers J, Sproul D, Lam EW. Gong C, et al. Among authors: khoo us. Oncogene. 2015 Sep 24;34(39):5012-24. doi: 10.1038/onc.2014.421. Epub 2014 Dec 22. Oncogene. 2015. PMID: 25531315 Free PMC article.

2

Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer.

Khoo US, Ozcelik H, Cheung AN, Chow LW, Ngan HY, Done SJ, Liang AC, Chan VW, Au GK, Ng WF, Poon CS, Leung YF, Loong F, Ip P, Chan GS, Andrulis IL, Lu J, Ho FC. Khoo US, et al. Oncogene. 1999 Aug 12;18(32):4643-6. doi: 10.1038/sj.onc.1202847. Oncogene. 1999. PMID: 10467410

3

Functional polymorphisms in the BRCA1 promoter influence transcription and are associated with decreased risk for breast cancer in Chinese women.

Chan KY, Liu W, Long JR, Yip SP, Chan SY, Shu XO, Chua DT, Cheung AN, Ching JC, Cai H, Au GK, Chan M, Foo W, Ngan HY, Gao YT, Ngan ES, Garcia-Barceló MM, Zheng W, Khoo US. Chan KY, et al. Among authors: khoo us. J Med Genet. 2009 Jan;46(1):32-9. doi: 10.1136/jmg.2007.057174. Epub 2008 Sep 9. J Med Genet. 2009. PMID: 18782836 Free PMC article.

4

FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer.

Karadedou CT, Gomes AR, Chen J, Petkovic M, Ho KK, Zwolinska AK, Feltes A, Wong SY, Chan KY, Cheung YN, Tsang JW, Brosens JJ, Khoo US, Lam EW. Karadedou CT, et al. Among authors: khoo us. Oncogene. 2012 Apr 5;31(14):1845-58. doi: 10.1038/onc.2011.368. Epub 2011 Aug 22. Oncogene. 2012. PMID: 21860419 Free PMC article.

5

FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance.

Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes AR, Yagüe E, Monteiro LJ, Kongsema M, Zona S, Man EP, Tsang JW, Coombes RC, Wu KJ, Khoo US, Medema RH, Freire R, Lam EW. Khongkow P, et al. Among authors: khoo us. Oncogene. 2014 Aug 7;33(32):4144-55. doi: 10.1038/onc.2013.457. Epub 2013 Oct 21. Oncogene. 2014. PMID: 24141789 Free PMC article.

6

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.

Khongkow P, Gomes AR, Gong C, Man EP, Tsang JW, Zhao F, Monteiro LJ, Coombes RC, Medema RH, Khoo US, Lam EW. Khongkow P, et al. Among authors: khoo us. Oncogene. 2016 Feb 25;35(8):990-1002. doi: 10.1038/onc.2015.152. Epub 2015 May 11. Oncogene. 2016. PMID: 25961928 Free PMC article.

7

OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance.

Karunarathna U, Kongsema M, Zona S, Gong C, Cabrera E, Gomes AR, Man EP, Khongkow P, Tsang JW, Khoo US, Medema RH, Freire R, Lam EW. Karunarathna U, et al. Among authors: khoo us. Oncogene. 2016 Mar 17;35(11):1433-44. doi: 10.1038/onc.2015.208. Epub 2015 Jul 6. Oncogene. 2016. PMID: 26148240 Free PMC article.

8

Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer.

Nestal de Moraes G, Khongkow P, Gong C, Yao S, Gomes AR, Ji Z, Kandola N, Delbue D, Man EP, Khoo US, Sharrocks AD, Lam EW. Nestal de Moraes G, et al. Among authors: khoo us. Oncogenesis. 2015 Sep 7;4(9):e167. doi: 10.1038/oncsis.2015.26. Oncogenesis. 2015. PMID: 26344694 Free PMC article.

9

BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer.

Gong C, Yao S, Gomes AR, Man EP, Lee HJ, Gong G, Chang S, Kim SB, Fujino K, Kim SW, Park SK, Lee JW, Lee MH; KOHBRA study group; Khoo US, Lam EW. Gong C, et al. Among authors: khoo us. Oncogenesis. 2016 Apr 4;5(4):e214. doi: 10.1038/oncsis.2016.23. Oncogenesis. 2016. PMID: 27043660 Free PMC article.

10

RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment.

Kongsema M, Zona S, Karunarathna U, Cabrera E, Man EP, Yao S, Shibakawa A, Khoo US, Medema RH, Freire R, Lam EW. Kongsema M, et al. Among authors: khoo us. Oncogenesis. 2016 Aug 15;5(8):e252. doi: 10.1038/oncsis.2016.57. Oncogenesis. 2016. PMID: 27526106 Free PMC article.

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