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Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.
Witt RM, Hecht ML, Pazyra-Murphy MF, Cohen SM, Noti C, van Kuppevelt TH, Fuller M, Chan JA, Hopwood JJ, Seeberger PH, Segal RA. Witt RM, et al. Among authors: chan ja. J Biol Chem. 2013 Sep 6;288(36):26275-26288. doi: 10.1074/jbc.M112.438937. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867465 Free PMC article.
An in vivo patient-derived model of endogenous IDH1-mutant glioma.
Luchman HA, Stechishin OD, Dang NH, Blough MD, Chesnelong C, Kelly JJ, Nguyen SA, Chan JA, Weljie AM, Cairncross JG, Weiss S. Luchman HA, et al. Among authors: chan ja. Neuro Oncol. 2012 Feb;14(2):184-91. doi: 10.1093/neuonc/nor207. Epub 2011 Dec 13. Neuro Oncol. 2012. PMID: 22166263 Free PMC article.
Lactate dehydrogenase A silencing in IDH mutant gliomas.
Chesnelong C, Chaumeil MM, Blough MD, Al-Najjar M, Stechishin OD, Chan JA, Pieper RO, Ronen SM, Weiss S, Luchman HA, Cairncross JG. Chesnelong C, et al. Among authors: chan ja. Neuro Oncol. 2014 May;16(5):686-95. doi: 10.1093/neuonc/not243. Epub 2013 Dec 22. Neuro Oncol. 2014. PMID: 24366912 Free PMC article.
263 results