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14 results

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Page 1
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.
Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan JJ, Botas J, Fischer DF, Svendsen CN, Munoz-Sanjuan I, Yang XW. Lu XH, et al. Among authors: fratantoni sa. Sci Transl Med. 2014 Dec 24;6(268):268ra178. doi: 10.1126/scitranslmed.3010523. Sci Transl Med. 2014. PMID: 25540325
A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.
Todd D, Gowers I, Dowler SJ, Wall MD, McAllister G, Fischer DF, Dijkstra S, Fratantoni SA, van de Bospoort R, Veenman-Koepke J, Flynn G, Arjomand J, Dominguez C, Munoz-Sanjuan I, Wityak J, Bard JA. Todd D, et al. Among authors: fratantoni sa. PLoS One. 2014 Feb 4;9(2):e87923. doi: 10.1371/journal.pone.0087923. eCollection 2014. PLoS One. 2014. PMID: 24503862 Free PMC article.
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.
Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Van Houdt WJ, et al. Among authors: fratantoni sa. Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25. Mol Cell Proteomics. 2011. PMID: 21788403 Free PMC article.
The proteome of the locus ceruleus in Parkinson's disease: relevance to pathogenesis.
van Dijk KD, Berendse HW, Drukarch B, Fratantoni SA, Pham TV, Piersma SR, Huisman E, Brevé JJ, Groenewegen HJ, Jimenez CR, van de Berg WD. van Dijk KD, et al. Among authors: fratantoni sa. Brain Pathol. 2012 Jul;22(4):485-98. doi: 10.1111/j.1750-3639.2011.00540.x. Epub 2011 Nov 8. Brain Pathol. 2012. PMID: 21988495 Free PMC article.
PPIB mutations cause severe osteogenesis imperfecta.
van Dijk FS, Nesbitt IM, Zwikstra EH, Nikkels PG, Piersma SR, Fratantoni SA, Jimenez CR, Huizer M, Morsman AC, Cobben JM, van Roij MH, Elting MW, Verbeke JI, Wijnaendts LC, Shaw NJ, Högler W, McKeown C, Sistermans EA, Dalton A, Meijers-Heijboer H, Pals G. van Dijk FS, et al. Among authors: fratantoni sa. Am J Hum Genet. 2009 Oct;85(4):521-7. doi: 10.1016/j.ajhg.2009.09.001. Epub 2009 Sep 24. Am J Hum Genet. 2009. PMID: 19781681 Free PMC article.
New high affinity H3 receptor agonists without a basic side chain.
Kitbunnadaj R, Hoffmann M, Fratantoni SA, Bongers G, Bakker RA, Wieland K, el Jilali A, De Esch IJ, Menge WM, Timmerman H, Leurs R. Kitbunnadaj R, et al. Among authors: fratantoni sa. Bioorg Med Chem. 2005 Dec 1;13(23):6309-23. doi: 10.1016/j.bmc.2005.09.002. Epub 2005 Oct 5. Bioorg Med Chem. 2005. PMID: 16213736
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