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Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, Osterman AL, Cronan JE, Jacobson MP, Gerlt JA, Almo SC. Vetting MW, et al. Biochemistry. 2015 Jan 27;54(3):909-31. doi: 10.1021/bi501388y. Epub 2015 Jan 16. Biochemistry. 2015. PMID: 25540822 Free PMC article.
Functional assignment of multiple catabolic pathways for D-apiose.
Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA. Carter MS, et al. Nat Chem Biol. 2018 Jul;14(7):696-705. doi: 10.1038/s41589-018-0067-7. Epub 2018 Jun 4. Nat Chem Biol. 2018. PMID: 29867142 Free PMC article.
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.
Zhang X, Carter MS, Vetting MW, San Francisco B, Zhao S, Al-Obaidi NF, Solbiati JO, Thiaville JJ, de Crécy-Lagard V, Jacobson MP, Almo SC, Gerlt JA. Zhang X, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4161-9. doi: 10.1073/pnas.1605546113. Epub 2016 Jul 11. Proc Natl Acad Sci U S A. 2016. PMID: 27402745 Free PMC article.
Prediction of enzymatic pathways by integrative pathway mapping.
Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A. Calhoun S, et al. Elife. 2018 Jan 29;7:e31097. doi: 10.7554/eLife.31097. Elife. 2018. PMID: 29377793 Free PMC article.
Novel Metabolic Pathways and Regulons for Hexuronate Utilization in Proteobacteria.
Bouvier JT, Sernova NV, Ghasempur S, Rodionova IA, Vetting MW, Al-Obaidi NF, Almo SC, Gerlt JA, Rodionov DA. Bouvier JT, et al. Among authors: al obaidi nf. J Bacteriol. 2018 Dec 20;201(2):e00431-18. doi: 10.1128/JB.00431-18. Print 2019 Jan 15. J Bacteriol. 2018. PMID: 30249705 Free PMC article.
32 results