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Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, Osterman AL, Cronan JE, Jacobson MP, Gerlt JA, Almo SC. Vetting MW, et al. Among authors: kim j. Biochemistry. 2015 Jan 27;54(3):909-31. doi: 10.1021/bi501388y. Epub 2015 Jan 16. Biochemistry. 2015. PMID: 25540822 Free PMC article.
The gate that governs sulfotransferase selectivity.
Cook I, Wang T, Almo SC, Kim J, Falany CN, Leyh TS. Cook I, et al. Among authors: kim j. Biochemistry. 2013 Jan 15;52(2):415-24. doi: 10.1021/bi301492j. Epub 2012 Dec 28. Biochemistry. 2013. PMID: 23256751 Free PMC article.
Structure-guided discovery of new deaminase enzymes.
Hitchcock DS, Fan H, Kim J, Vetting M, Hillerich B, Seidel RD, Almo SC, Shoichet BK, Sali A, Raushel FM. Hitchcock DS, et al. Among authors: kim j. J Am Chem Soc. 2013 Sep 18;135(37):13927-33. doi: 10.1021/ja4066078. Epub 2013 Sep 4. J Am Chem Soc. 2013. PMID: 23968233 Free PMC article.
Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.
Mashiyama ST, Malabanan MM, Akiva E, Bhosle R, Branch MC, Hillerich B, Jagessar K, Kim J, Patskovsky Y, Seidel RD, Stead M, Toro R, Vetting MW, Almo SC, Armstrong RN, Babbitt PC. Mashiyama ST, et al. Among authors: kim j. PLoS Biol. 2014 Apr 22;12(4):e1001843. doi: 10.1371/journal.pbio.1001843. eCollection 2014 Apr. PLoS Biol. 2014. PMID: 24756107 Free PMC article.
Testing the sulfotransferase molecular pore hypothesis.
Cook I, Wang T, Almo SC, Kim J, Falany CN, Leyh TS. Cook I, et al. Among authors: kim j. J Biol Chem. 2013 Mar 22;288(12):8619-8626. doi: 10.1074/jbc.M112.445015. Epub 2013 Jan 28. J Biol Chem. 2013. PMID: 23362278 Free PMC article.
135,308 results
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