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Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, Osterman AL, Cronan JE, Jacobson MP, Gerlt JA, Almo SC. Vetting MW, et al. Among authors: love jd. Biochemistry. 2015 Jan 27;54(3):909-31. doi: 10.1021/bi501388y. Epub 2015 Jan 16. Biochemistry. 2015. PMID: 25540822 Free PMC article.
Panoramic view of a superfamily of phosphatases through substrate profiling.
Huang H, Pandya C, Liu C, Al-Obaidi NF, Wang M, Zheng L, Toews Keating S, Aono M, Love JD, Evans B, Seidel RD, Hillerich BS, Garforth SJ, Almo SC, Mariano PS, Dunaway-Mariano D, Allen KN, Farelli JD. Huang H, et al. Among authors: love jd. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E1974-83. doi: 10.1073/pnas.1423570112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848029 Free PMC article.
Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.
Garrett-Thomson SC, Massimi A, Fedorov EV, Bonanno JB, Scandiuzzi L, Hillerich B, Seidel RD 3rd, Love JD, Garforth SJ, Guha C, Almo SC. Garrett-Thomson SC, et al. Among authors: love jd. PLoS One. 2020 Jun 4;15(6):e0233578. doi: 10.1371/journal.pone.0233578. eCollection 2020. PLoS One. 2020. PMID: 32497097 Free PMC article.
Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile.
Boskovic ZV, Kemp MM, Freedy AM, Viswanathan VS, Pop MS, Fuller JH, Martinez NM, Figueroa Lazú SO, Hong JA, Lewis TA, Calarese D, Love JD, Vetere A, Almo SC, Schreiber SL, Koehler AN. Boskovic ZV, et al. Among authors: love jd. ACS Chem Biol. 2016 Jul 15;11(7):1844-51. doi: 10.1021/acschembio.6b00012. Epub 2016 Apr 29. ACS Chem Biol. 2016. PMID: 27064299
A naturally occurring antiviral ribonucleotide encoded by the human genome.
Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD, Chandran K, Bresnick AR, Cameron CE, Almo SC. Gizzi AS, et al. Among authors: love jd. Nature. 2018 Jun;558(7711):610-614. doi: 10.1038/s41586-018-0238-4. Epub 2018 Jun 20. Nature. 2018. PMID: 29925952 Free PMC article.
Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
Soniat M, Sampathkumar P, Collett G, Gizzi AS, Banu RN, Bhosle RC, Chamala S, Chowdhury S, Fiser A, Glenn AS, Hammonds J, Hillerich B, Khafizov K, Love JD, Matikainen B, Seidel RD, Toro R, Rajesh Kumar P, Bonanno JB, Chook YM, Almo SC. Soniat M, et al. Among authors: love jd. J Struct Funct Genomics. 2013 Jun;14(2):31-5. doi: 10.1007/s10969-013-9150-1. Epub 2013 Mar 28. J Struct Funct Genomics. 2013. PMID: 23535894 Free PMC article.
81 results