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Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, Osterman AL, Cronan JE, Jacobson MP, Gerlt JA, Almo SC. Vetting MW, et al. Among authors: san francisco b. Biochemistry. 2015 Jan 27;54(3):909-31. doi: 10.1021/bi501388y. Epub 2015 Jan 16. Biochemistry. 2015. PMID: 25540822 Free PMC article.
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.
Zhang X, Carter MS, Vetting MW, San Francisco B, Zhao S, Al-Obaidi NF, Solbiati JO, Thiaville JJ, de Crécy-Lagard V, Jacobson MP, Almo SC, Gerlt JA. Zhang X, et al. Among authors: san francisco b. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4161-9. doi: 10.1073/pnas.1605546113. Epub 2016 Jul 11. Proc Natl Acad Sci U S A. 2016. PMID: 27402745 Free PMC article.
Prediction of enzymatic pathways by integrative pathway mapping.
Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A. Calhoun S, et al. Among authors: san francisco b. Elife. 2018 Jan 29;7:e31097. doi: 10.7554/eLife.31097. Elife. 2018. PMID: 29377793 Free PMC article.
A conserved haem redox and trafficking pathway for cofactor attachment.
Richard-Fogal CL, Frawley ER, Bonner ER, Zhu H, San Francisco B, Kranz RG. Richard-Fogal CL, et al. Among authors: san francisco b. EMBO J. 2009 Aug 19;28(16):2349-59. doi: 10.1038/emboj.2009.189. Epub 2009 Jul 23. EMBO J. 2009. PMID: 19629033 Free PMC article.
15 results