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Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, Osterman AL, Cronan JE, Jacobson MP, Gerlt JA, Almo SC. Vetting MW, et al. Among authors: wichelecki dj. Biochemistry. 2015 Jan 27;54(3):909-31. doi: 10.1021/bi501388y. Epub 2015 Jan 16. Biochemistry. 2015. PMID: 25540822 Free PMC article.
Prediction of enzymatic pathways by integrative pathway mapping.
Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A. Calhoun S, et al. Among authors: wichelecki dj. Elife. 2018 Jan 29;7:e31097. doi: 10.7554/eLife.31097. Elife. 2018. PMID: 29377793 Free PMC article.
Detection of liposome lysis utilizing an enzyme-substrate system.
Wichelecki DJ, McNew TM, Aygun A, Torrey K, Stephenson LD. Wichelecki DJ, et al. Appl Biochem Biotechnol. 2011 Sep;165(2):548-58. doi: 10.1007/s12010-011-9274-3. Epub 2011 May 24. Appl Biochem Biotechnol. 2011. PMID: 21607678