Wongvipat J - Search Results

1

Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.

Schwartz S, Wongvipat J, Trigwell CB, Hancox U, Carver BS, Rodrik-Outmezguine V, Will M, Yellen P, de Stanchina E, Baselga J, Scher HI, Barry ST, Sawyers CL, Chandarlapaty S, Rosen N. Schwartz S, et al. Among authors: wongvipat j. Cancer Cell. 2015 Jan 12;27(1):109-22. doi: 10.1016/j.ccell.2014.11.008. Epub 2014 Dec 24. Cancer Cell. 2015. PMID: 25544636 Free PMC article.

2

Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Ellwood-Yen K, et al. Among authors: wongvipat j. Cancer Cell. 2003 Sep;4(3):223-38. doi: 10.1016/s1535-6108(03)00197-1. Cancer Cell. 2003. PMID: 14522256 Free article.

3

HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability.

Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. Mellinghoff IK, et al. Among authors: wongvipat j. Cancer Cell. 2004 Nov;6(5):517-27. doi: 10.1016/j.ccr.2004.09.031. Cancer Cell. 2004. PMID: 15542435 Free article.

4

Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line.

Watson PA, Ellwood-Yen K, King JC, Wongvipat J, Lebeau MM, Sawyers CL. Watson PA, et al. Among authors: wongvipat j. Cancer Res. 2005 Dec 15;65(24):11565-71. doi: 10.1158/0008-5472.CAN-05-3441. Cancer Res. 2005. PMID: 16357166

5

Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens.

Ellwood-Yen K, Wongvipat J, Sawyers C. Ellwood-Yen K, et al. Among authors: wongvipat j. Cancer Res. 2006 Nov 1;66(21):10513-6. doi: 10.1158/0008-5472.CAN-06-1397. Cancer Res. 2006. PMID: 17079473

6

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL. Tran C, et al. Among authors: wongvipat j. Science. 2009 May 8;324(5928):787-90. doi: 10.1126/science.1168175. Epub 2009 Apr 9. Science. 2009. PMID: 19359544 Free PMC article. Clinical Trial.

7

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.

King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL. King JC, et al. Among authors: wongvipat j. Nat Genet. 2009 May;41(5):524-6. doi: 10.1038/ng.371. Epub 2009 Apr 26. Nat Genet. 2009. PMID: 19396167 Free PMC article.

8

Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC).

Jung ME, Ouk S, Yoo D, Sawyers CL, Chen C, Tran C, Wongvipat J. Jung ME, et al. Among authors: wongvipat j. J Med Chem. 2010 Apr 8;53(7):2779-96. doi: 10.1021/jm901488g. J Med Chem. 2010. PMID: 20218717 Free PMC article.

9

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor.

Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A, Kim K, Sawyers CL. Watson PA, et al. Among authors: wongvipat j. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16759-65. doi: 10.1073/pnas.1012443107. Epub 2010 Sep 7. Proc Natl Acad Sci U S A. 2010. PMID: 20823238 Free PMC article.

10

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.

Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL. Chi P, et al. Among authors: wongvipat j. Nature. 2010 Oct 14;467(7317):849-53. doi: 10.1038/nature09409. Epub 2010 Oct 3. Nature. 2010. PMID: 20927104 Free PMC article.

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