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Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.
Kinross KM, Montgomery KG, Mangiafico SP, Hare LM, Kleinschmidt M, Bywater MJ, Poulton IJ, Vrahnas C, Henneicke H, Malaterre J, Waring PM, Cullinane C, Sims NA, McArthur GA, Andrikopoulos S, Phillips WA. Kinross KM, et al. Among authors: sims na. FASEB J. 2015 Apr;29(4):1426-34. doi: 10.1096/fj.14-262782. Epub 2014 Dec 30. FASEB J. 2015. PMID: 25550458
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.
Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, Gutierrez GM, Piscopo DM, Carty SA, Hinds PW. Thomas DM, et al. Among authors: sims na. J Cell Biol. 2004 Dec 6;167(5):925-34. doi: 10.1083/jcb.200409187. J Cell Biol. 2004. PMID: 15583032 Free PMC article.
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice.
Walker EC, McGregor NE, Poulton IJ, Solano M, Pompolo S, Fernandes TJ, Constable MJ, Nicholson GC, Zhang JG, Nicola NA, Gillespie MT, Martin TJ, Sims NA. Walker EC, et al. Among authors: sims na. J Clin Invest. 2010 Feb;120(2):582-92. doi: 10.1172/JCI40568. Epub 2010 Jan 4. J Clin Invest. 2010. PMID: 20051625 Free PMC article.
201 results