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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF. Deng K, et al. Among authors: durand cm. Nature. 2015 Jan 15;517(7534):381-5. doi: 10.1038/nature14053. Epub 2015 Jan 7. Nature. 2015. PMID: 25561180 Free PMC article.
Identification of nevirapine-resistant HIV-1 in the latent reservoir after single-dose nevirapine to prevent mother-to-child transmission of HIV-1.
Wind-Rotolo M, Durand C, Cranmer L, Reid A, Martinson N, Doherty M, Jilek BL, Kagaayi J, Kizza A, Pillay V, Laeyendecker O, Reynolds SJ, Eshleman SH, Lau B, Ray SC, Siliciano JD, Quinn TC, Siliciano RF. Wind-Rotolo M, et al. J Infect Dis. 2009 May 1;199(9):1301-9. doi: 10.1086/597759. J Infect Dis. 2009. PMID: 19338474 Free PMC article.
HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy.
Durand CM, Ghiaur G, Siliciano JD, Rabi SA, Eisele EE, Salgado M, Shan L, Lai JF, Zhang H, Margolick J, Jones RJ, Gallant JE, Ambinder RF, Siliciano RF. Durand CM, et al. J Infect Dis. 2012 Mar 15;205(6):1014-8. doi: 10.1093/infdis/jir884. Epub 2012 Jan 24. J Infect Dis. 2012. PMID: 22275402 Free PMC article.
Developing strategies for HIV-1 eradication.
Durand CM, Blankson JN, Siliciano RF. Durand CM, et al. Trends Immunol. 2012 Nov;33(11):554-62. doi: 10.1016/j.it.2012.07.001. Epub 2012 Aug 3. Trends Immunol. 2012. PMID: 22867874 Free PMC article. Review.
HIV cure: knocking on the door.
Durand CM, Flexner C. Durand CM, et al. Clin Pharmacol Ther. 2013 May;93(5):382-4. doi: 10.1038/clpt.2013.22. Clin Pharmacol Ther. 2013. PMID: 23598454
Dual zinc-finger nucleases block HIV infection.
Durand CM, Siliciano RF. Durand CM, et al. Blood. 2014 Jan 2;123(1):2-3. doi: 10.1182/blood-2013-11-535542. Blood. 2014. PMID: 24385492 Free article. No abstract available.
228 results