Klein CE - Search Results

1

A novel ritonavir paediatric powder formulation is bioequivalent to ritonavir oral solution with a similar food effect.

Salem AH, Chiu YL, Valdes JM, Nilius AM, Klein CE. Salem AH, et al. Among authors: klein ce. Antivir Ther. 2015;20(4):425-32. doi: 10.3851/IMP2932. Epub 2015 Jan 9. Antivir Ther. 2015. PMID: 25573904 Clinical Trial.

2

The tablet formulation of lopinavir/ritonavir provides similar bioavailability to the soft-gelatin capsule formulation with less pharmacokinetic variability and diminished food effect.

Klein CE, Chiu YL, Awni W, Zhu T, Heuser RS, Doan T, Breitenbach J, Morris JB, Brun SC, Hanna GJ. Klein CE, et al. J Acquir Immune Defic Syndr. 2007 Apr 1;44(4):401-10. doi: 10.1097/QAI.0b013e31803133c5. J Acquir Immune Defic Syndr. 2007. PMID: 17224848 Clinical Trial.

3

Lack of effect of gastric acid-reducing agents on the pharmacokinetics of lopinavir/ritonavir in HIV-infected patients.

Chiu YL, Klein CE, Woodward WC, King KR, Naylor C, Awni W, Brun S. Chiu YL, et al. Among authors: klein ce. AIDS Patient Care STDS. 2007 Apr;21(4):247-51. doi: 10.1089/apc.2006.0120. AIDS Patient Care STDS. 2007. PMID: 17461719

4

Effects of acid-reducing agents on the pharmacokinetics of lopinavir/ritonavir and ritonavir-boosted atazanavir.

Klein CE, Chiu YL, Cai Y, Beck K, King KR, Causemaker SJ, Doan T, Esslinger HU, Podsadecki TJ, Hanna GJ. Klein CE, et al. J Clin Pharmacol. 2008 May;48(5):553-62. doi: 10.1177/0091270007313392. J Clin Pharmacol. 2008. PMID: 18440920 Clinical Trial.

5

Predictors of loss of virologic response in subjects who simplified to lopinavir/ritonavir monotherapy from lopinavir/ritonavir plus zidovudine/lamivudine.

Campo RE, Da Silva BA, Cotte L, Gathe JC, Gazzard B, Hicks CB, Klein CE, Chiu YL, King MS, Bernstein BM. Campo RE, et al. Among authors: klein ce. AIDS Res Hum Retroviruses. 2009 Mar;25(3):269-75. doi: 10.1089/aid.2008.0217. AIDS Res Hum Retroviruses. 2009. PMID: 19292590 Clinical Trial.

6

Pharmacokinetics and safety of the lopinavir/ritonavir tablet 500/125 mg twice daily coadministered with efavirenz in healthy adult participants.

Ng J, Chiu YL, Awni W, Bernstein B, Causemaker SJ, Klein CE. Ng J, et al. Among authors: klein ce. J Clin Pharmacol. 2012 Aug;52(8):1248-54. doi: 10.1177/0091270011410568. Epub 2011 Jun 30. J Clin Pharmacol. 2012. PMID: 21719718

7

No Need for Lopinavir Dose Adjustment during Pregnancy: a Population Pharmacokinetic and Exposure-Response Analysis in Pregnant and Nonpregnant HIV-Infected Subjects.

Salem AH, Jones AK, Santini-Oliveira M, Taylor GP, Patterson KB, Nilius AM, Klein CE. Salem AH, et al. Among authors: klein ce. Antimicrob Agents Chemother. 2015 Nov 2;60(1):400-8. doi: 10.1128/AAC.01197-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26525798 Free PMC article. Clinical Trial.

8

Pharmacokinetics and tolerability of paritaprevir, a direct acting antiviral agent for hepatitis C virus treatment, with and without ritonavir in healthy volunteers.

Menon RM, Klein CE, Podsadecki TJ, Chiu YL, Dutta S, Awni WM. Menon RM, et al. Among authors: klein ce. Br J Clin Pharmacol. 2016 May;81(5):929-40. doi: 10.1111/bcp.12873. Epub 2016 Feb 24. Br J Clin Pharmacol. 2016. PMID: 26710243 Free PMC article. Clinical Trial.

9

Elagolix Suppresses Ovulation in a Dose-Dependent Manner: Results From a 3-Month, Randomized Study in Ovulatory Women.

Archer DF, Ng J, Chwalisz K, Chiu YL, Feinberg EC, Miller CE, Feldman RA, Klein CE. Archer DF, et al. Among authors: klein ce. J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgz086. doi: 10.1210/clinem/dgz086. J Clin Endocrinol Metab. 2020. PMID: 31650182 Clinical Trial.

10

Pharmacokinetic and Pharmacodynamic Profiles of Ethinylestradiol/Norgestimate Combination or Norethindrone upon Coadministration with Elagolix 150 mg Once Daily in Healthy Premenopausal Women.

Feldman RA, Chiu YL, Klein CE, Ng J. Feldman RA, et al. Among authors: klein ce. Clin Pharmacokinet. 2021 Aug;60(8):1003-1013. doi: 10.1007/s40262-021-00989-0. Epub 2021 Mar 22. Clin Pharmacokinet. 2021. PMID: 33748934 Free PMC article.

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