Jacobsen RN - Search Results

1

HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.

Forristal CE, Nowlan B, Jacobsen RN, Barbier V, Walkinshaw G, Walkley CR, Winkler IG, Levesque JP. Forristal CE, et al. Among authors: jacobsen rn. Leukemia. 2015 Jun;29(6):1366-78. doi: 10.1038/leu.2015.8. Epub 2015 Jan 12. Leukemia. 2015. PMID: 25578474 Free PMC article.

2

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance.

Winkler IG, Barbier V, Nowlan B, Jacobsen RN, Forristal CE, Patton JT, Magnani JL, Lévesque JP. Winkler IG, et al. Among authors: jacobsen rn. Nat Med. 2012 Nov;18(11):1651-7. doi: 10.1038/nm.2969. Epub 2012 Oct 21. Nat Med. 2012. PMID: 23086476

3

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation.

Winkler IG, Pettit AR, Raggatt LJ, Jacobsen RN, Forristal CE, Barbier V, Nowlan B, Cisterne A, Bendall LJ, Sims NA, Lévesque JP. Winkler IG, et al. Among authors: jacobsen rn. Leukemia. 2012 Jul;26(7):1594-601. doi: 10.1038/leu.2012.17. Epub 2012 Jan 23. Leukemia. 2012. PMID: 22266913

4

Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80(+)VCAM1(+)CD169(+)ER-HR3(+)Ly6G(+) erythroid island macrophages in the mouse.

Jacobsen RN, Forristal CE, Raggatt LJ, Nowlan B, Barbier V, Kaur S, van Rooijen N, Winkler IG, Pettit AR, Levesque JP. Jacobsen RN, et al. Exp Hematol. 2014 Jul;42(7):547-61.e4. doi: 10.1016/j.exphem.2014.03.009. Epub 2014 Apr 8. Exp Hematol. 2014. PMID: 24721610 Free article.

5

Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse.

Jacobsen RN, Nowlan B, Brunck ME, Barbier V, Winkler IG, Levesque JP. Jacobsen RN, et al. Exp Hematol. 2016 Mar;44(3):207-12.e4. doi: 10.1016/j.exphem.2015.11.004. Epub 2015 Dec 1. Exp Hematol. 2016. PMID: 26607596 Free article.

6

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment.

Kaur S, Raggatt LJ, Millard SM, Wu AC, Batoon L, Jacobsen RN, Winkler IG, MacDonald KP, Perkins AC, Hume DA, Levesque JP, Pettit AR. Kaur S, et al. Among authors: jacobsen rn. Blood. 2018 Aug 16;132(7):735-749. doi: 10.1182/blood-2018-01-829663. Epub 2018 Jun 26. Blood. 2018. PMID: 29945953 Free article.

7

Macrophages and regulation of erythropoiesis.

Jacobsen RN, Perkins AC, Levesque JP. Jacobsen RN, et al. Curr Opin Hematol. 2015 May;22(3):212-9. doi: 10.1097/MOH.0000000000000131. Curr Opin Hematol. 2015. PMID: 25693142

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