Jang HH - Search Results

1

Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison.

Shah MB, Wilderman PR, Liu J, Jang HH, Zhang Q, Stout CD, Halpert JR. Shah MB, et al. Among authors: jang hh. Mol Pharmacol. 2015 Apr;87(4):649-59. doi: 10.1124/mol.114.097014. Epub 2015 Jan 13. Mol Pharmacol. 2015. PMID: 25585967 Free PMC article.

2

The role of cytochrome P450 2B6 and 2B4 substrate access channel residues predicted based on crystal structures of the amlodipine complexes.

Jang HH, Davydov DR, Lee GY, Yun CH, Halpert JR. Jang HH, et al. Arch Biochem Biophys. 2014 Mar 1;545:100-7. doi: 10.1016/j.abb.2014.01.008. Epub 2014 Jan 18. Arch Biochem Biophys. 2014. PMID: 24445070 Free PMC article.

3

Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes.

Jang HH, Liu J, Lee GY, Halpert JR, Wilderman PR. Jang HH, et al. Arch Biochem Biophys. 2015 Oct 15;584:61-9. doi: 10.1016/j.abb.2015.08.007. Epub 2015 Aug 28. Arch Biochem Biophys. 2015. PMID: 26319176 Free PMC article.

4

Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry.

Shah MB, Jang HH, Wilderman PR, Lee D, Li S, Zhang Q, Stout CD, Halpert JR. Shah MB, et al. Among authors: jang hh. Biophys Chem. 2016 Sep;216:1-8. doi: 10.1016/j.bpc.2016.05.007. Epub 2016 Jun 1. Biophys Chem. 2016. PMID: 27280734 Free PMC article.

5

Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6.

Wilderman PR, Shah MB, Jang HH, Stout CD, Halpert JR. Wilderman PR, et al. Among authors: jang hh. J Am Chem Soc. 2013 Jul 17;135(28):10433-40. doi: 10.1021/ja403042k. Epub 2013 Jul 3. J Am Chem Soc. 2013. PMID: 23786449 Free PMC article.

6

Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida.

Wilderman PR, Jang HH, Malenke JR, Salib M, Angermeier E, Lamime S, Dearing MD, Halpert JR. Wilderman PR, et al. Among authors: jang hh. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):393-401. doi: 10.1016/j.taap.2013.12.005. Epub 2013 Dec 19. Toxicol Appl Pharmacol. 2014. PMID: 24361551 Free PMC article.

7

Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme.

Wilderman PR, Gay SC, Jang HH, Zhang Q, Stout CD, Halpert JR. Wilderman PR, et al. Among authors: jang hh. FEBS J. 2012 May;279(9):1607-20. doi: 10.1111/j.1742-4658.2011.08411.x. Epub 2011 Nov 25. FEBS J. 2012. PMID: 22051155 Free PMC article.

8

X-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: insights into compensatory rearrangements of the binding pocket.

Shah MB, Jang HH, Zhang Q, David Stout C, Halpert JR. Shah MB, et al. Among authors: jang hh. Arch Biochem Biophys. 2013 Feb 15;530(2):64-72. doi: 10.1016/j.abb.2012.12.016. Epub 2013 Jan 4. Arch Biochem Biophys. 2013. PMID: 23296089 Free PMC article.

9

Functional and conformational modulation of human cytochrome P450 1B1 by anionic phospholipids.

Jang HH, Kim DH, Ahn T, Yun CH. Jang HH, et al. Arch Biochem Biophys. 2010 Jan 15;493(2):143-50. doi: 10.1016/j.abb.2009.10.012. Epub 2009 Oct 24. Arch Biochem Biophys. 2010. PMID: 19857456

10

Lateral segregation of anionic phospholipids in model membranes induced by cytochrome P450 2B1: bi-directional coupling between CYP2B1 and anionic phospholipid.

Kim KH, Kim DH, Jang HH, Kim M, Kim DH, Kim JS, Kim JI, Chae HZ, Ahn T, Yun CH. Kim KH, et al. Among authors: jang hh. Arch Biochem Biophys. 2007 Dec 15;468(2):226-33. doi: 10.1016/j.abb.2007.10.003. Epub 2007 Oct 12. Arch Biochem Biophys. 2007. PMID: 17980858

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