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Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition.
Hayek S, Pietrancosta N, Hovhannisyan AA, Alves de Sousa R, Bekaddour N, Ermellino L, Tramontano E, Arnould S, Sardet C, Dairou J, Diaz O, Lotteau V, Nisole S, Melikyan G, Herbeuval JP, Vidalain PO. Hayek S, et al. Among authors: herbeuval jp. Eur J Med Chem. 2020 Jan 15;186:111855. doi: 10.1016/j.ejmech.2019.111855. Epub 2019 Nov 6. Eur J Med Chem. 2020. PMID: 31740051
Plasmacytoid dendritic cells (pDCs) from HIV controllers produce interferon-α and differentiate into functional killer pDCs under HIV activation.
Barblu L, Machmach K, Gras C, Delfraissy JF, Boufassa F, Leal M, Ruiz-Mateos E, Lambotte O, Herbeuval JP; ANRS EP36 HIV Controllers Study Group. Barblu L, et al. Among authors: herbeuval jp. J Infect Dis. 2012 Sep 1;206(5):790-801. doi: 10.1093/infdis/jis384. Epub 2012 Jun 12. J Infect Dis. 2012. PMID: 22693234
66 results