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A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.
Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL. Sharma A, et al. Among authors: ghiassian sd. Hum Mol Genet. 2015 Jun 1;24(11):3005-20. doi: 10.1093/hmg/ddv001. Epub 2015 Jan 12. Hum Mol Genet. 2015. PMID: 25586491 Free PMC article.
Tissue Specificity of Human Disease Module.
Kitsak M, Sharma A, Menche J, Guney E, Ghiassian SD, Loscalzo J, Barabási AL. Kitsak M, et al. Among authors: ghiassian sd. Sci Rep. 2016 Oct 17;6:35241. doi: 10.1038/srep35241. Sci Rep. 2016. PMID: 27748412 Free PMC article.
Endophenotype Network Models: Common Core of Complex Diseases.
Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabási AL, Loscalzo J. Ghiassian SD, et al. Sci Rep. 2016 Jun 9;6:27414. doi: 10.1038/srep27414. Sci Rep. 2016. PMID: 27278246 Free PMC article.
A proteome-scale map of the human interactome network.
Rolland T, Taşan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Wanamaker SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabási AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP, Vidal M. Rolland T, et al. Among authors: ghiassian sd. Cell. 2014 Nov 20;159(5):1212-1226. doi: 10.1016/j.cell.2014.10.050. Cell. 2014. PMID: 25416956 Free PMC article.
Network medicine framework for identifying drug-repurposing opportunities for COVID-19.
Morselli Gysi D, do Valle Í, Zitnik M, Ameli A, Gan X, Varol O, Ghiassian SD, Patten JJ, Davey RA, Loscalzo J, Barabási AL. Morselli Gysi D, et al. Among authors: ghiassian sd. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2025581118. doi: 10.1073/pnas.2025581118. Proc Natl Acad Sci U S A. 2021. PMID: 33906951 Free PMC article.
NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review.
Oldham WM, Hemnes AR, Aldred MA, Barnard J, Brittain EL, Chan SY, Cheng F, Cho MH, Desai AA, Garcia JGN, Geraci MW, Ghiassian SD, Hall KT, Horn EM, Jain M, Kelly RS, Leopold JA, Lindstrom S, Modena BD, Nichols WC, Rhodes CJ, Sun W, Sweatt AJ, Vanderpool RR, Wilkins MR, Wilmot B, Zamanian RT, Fessel JP, Aggarwal NR, Loscalzo J, Xiao L. Oldham WM, et al. Among authors: ghiassian sd. J Am Coll Cardiol. 2021 Apr 27;77(16):2040-2052. doi: 10.1016/j.jacc.2021.02.056. J Am Coll Cardiol. 2021. PMID: 33888254 Free PMC article. Review.
RETRACTED: Network-based response module comprised of gene expression biomarkers predicts response to infliximab at treatment initiation in ulcerative colitis.
Ghiassian SD, Withers JB, Santolini M, Saleh A, Akmaev VR. Ghiassian SD, et al. Transl Res. 2022 Jan;239:35-43. doi: 10.1016/j.trsl.2021.04.010. Epub 2021 May 7. Transl Res. 2022. Retraction in: Transl Res. 2022 Jun;244:137. doi: 10.1016/j.trsl.2022.03.011 PMID: 33965585 Free article. Retracted.
17 results