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Oxidative stress causes heart failure with impaired mitochondrial respiration.
Nojiri H, Shimizu T, Funakoshi M, Yamaguchi O, Zhou H, Kawakami S, Ohta Y, Sami M, Tachibana T, Ishikawa H, Kurosawa H, Kahn RC, Otsu K, Shirasawa T. Nojiri H, et al. Among authors: shimizu t. J Biol Chem. 2006 Nov 3;281(44):33789-801. doi: 10.1074/jbc.M602118200. Epub 2006 Sep 6. J Biol Chem. 2006. PMID: 16959785 Free article.
Antioxidant, EUK-8, prevents murine dilated cardiomyopathy.
Kawakami S, Matsuda A, Sunagawa T, Noda Y, Kaneko T, Tahara S, Hiraumi Y, Adachi S, Matsui H, Ando K, Fujita T, Maruyama N, Shirasawa T, Shimizu T. Kawakami S, et al. Among authors: shimizu t. Circ J. 2009 Nov;73(11):2125-34. doi: 10.1253/circj.cj-09-0204. Epub 2009 Sep 14. Circ J. 2009. PMID: 19749480 Free article.
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