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Pharmacological activation of myosin II paralogs to correct cell mechanics defects.
Surcel A, Ng WP, West-Foyle H, Zhu Q, Ren Y, Avery LB, Krenc AK, Meyers DJ, Rock RS, Anders RA, Freel Meyers CL, Robinson DN. Surcel A, et al. Among authors: rock rs. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1428-33. doi: 10.1073/pnas.1412592112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605895 Free PMC article.
A myosin motor that selects bundled actin for motility.
Nagy S, Ricca BL, Norstrom MF, Courson DS, Brawley CM, Smithback PA, Rock RS. Nagy S, et al. Among authors: rock rs. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9616-20. doi: 10.1073/pnas.0802592105. Epub 2008 Jul 3. Proc Natl Acad Sci U S A. 2008. PMID: 18599451 Free PMC article.
4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis.
Bryan DS, Stack M, Krysztofiak K, Cichoń U, Thomas DG, Surcel A, Schiffhauer ES, Beckett MA, Khodarev NN, Xue L, Poli EC, Pearson AT, Posner MC, Robinson DN, Rock RS, Weichselbaum RR. Bryan DS, et al. Among authors: rock rs. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22423-22429. doi: 10.1073/pnas.2014639117. Epub 2020 Aug 26. Proc Natl Acad Sci U S A. 2020. PMID: 32848073 Free PMC article.
46 results