Poulsen SA - Search Results

1

Saccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.

Mahon BP, Hendon AM, Driscoll JM, Rankin GM, Poulsen SA, Supuran CT, McKenna R. Mahon BP, et al. Among authors: poulsen sa. Bioorg Med Chem. 2015 Feb 15;23(4):849-54. doi: 10.1016/j.bmc.2014.12.030. Epub 2014 Dec 23. Bioorg Med Chem. 2015. PMID: 25614109 Free PMC article.

2

Screening a natural product-based combinatorial library using FTICR mass spectrometry.

Poulsen SA, Davis RA, Keys TG. Poulsen SA, et al. Bioorg Med Chem. 2006 Jan 15;14(2):510-5. doi: 10.1016/j.bmc.2005.08.030. Epub 2005 Sep 29. Bioorg Med Chem. 2006. PMID: 16198579

3

Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.

Poulsen SA, Bornaghi LF, Healy PC. Poulsen SA, et al. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. doi: 10.1016/j.bmcl.2005.08.113. Epub 2005 Oct 6. Bioorg Med Chem Lett. 2005. PMID: 16213706

4

Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis.

Poulsen SA, Bornaghi LF. Poulsen SA, et al. Bioorg Med Chem. 2006 May 15;14(10):3275-84. doi: 10.1016/j.bmc.2005.12.054. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431113 Free article.

5

A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".

Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. J Med Chem. 2006 Nov 2;49(22):6539-48. doi: 10.1021/jm060967z. J Med Chem. 2006. PMID: 17064072 Free article.

6

Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides.

Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. Bioorg Med Chem Lett. 2007 Feb 15;17(4):987-92. doi: 10.1016/j.bmcl.2006.11.046. Epub 2006 Nov 17. Bioorg Med Chem Lett. 2007. PMID: 17157501 Free article.

7

Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.

Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. J Med Chem. 2007 Apr 5;50(7):1651-7. doi: 10.1021/jm061320h. Epub 2007 Mar 8. J Med Chem. 2007. PMID: 17343373

8

Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.

Salmon AJ, Williams ML, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Salmon AJ, et al. Among authors: poulsen sa. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5032-5. doi: 10.1016/j.bmcl.2007.07.024. Epub 2007 Jul 19. Bioorg Med Chem Lett. 2007. PMID: 17681760

9

Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.

Wilkinson BL, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. J Med Chem. 2008 Mar 27;51(6):1945-53. doi: 10.1021/jm701426t. Epub 2008 Feb 29. J Med Chem. 2008. PMID: 18307288

10

Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives.

Poulsen SA, Wilkinson BL, Innocenti A, Vullo D, Supuran CT. Poulsen SA, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4624-7. doi: 10.1016/j.bmcl.2008.07.010. Epub 2008 Jul 10. Bioorg Med Chem Lett. 2008. PMID: 18644716

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