Qiu J - Search Results

1

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.

Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, Cleveland DW. Sun S, et al. Among authors: qiu h, qiu j. Nat Commun. 2015 Jan 27;6:6171. doi: 10.1038/ncomms7171. Nat Commun. 2015. PMID: 25625564 Free PMC article.

2

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.

Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterlé S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L. Scekic-Zahirovic J, et al. Among authors: qiu j. EMBO J. 2016 May 17;35(10):1077-97. doi: 10.15252/embj.201592559. Epub 2016 Mar 7. EMBO J. 2016. PMID: 26951610 Free PMC article.

3

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.

López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S. López-Erauskin J, et al. Among authors: qiu j. Neuron. 2018 Nov 21;100(4):816-830.e7. doi: 10.1016/j.neuron.2018.09.044. Epub 2018 Oct 18. Neuron. 2018. PMID: 30344044 Free PMC article.

4

Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing.

Pandit S, Zhou Y, Shiue L, Coutinho-Mansfield G, Li H, Qiu J, Huang J, Yeo GW, Ares M Jr, Fu XD. Pandit S, et al. Among authors: qiu j. Mol Cell. 2013 Apr 25;50(2):223-35. doi: 10.1016/j.molcel.2013.03.001. Epub 2013 Apr 4. Mol Cell. 2013. PMID: 23562324 Free PMC article.

5

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.

Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, Drenner K, Artates JW, McAlonis-Downes M, Markmiller S, Hutt KR, Pizzo DP, Cady J, Harms MB, Baloh RH, Vandenberg SR, Yeo GW, Fu XD, Bennett CF, Cleveland DW, Ravits J. Lagier-Tourenne C, et al. Among authors: qiu j. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4530-9. doi: 10.1073/pnas.1318835110. Epub 2013 Oct 29. Proc Natl Acad Sci U S A. 2013. PMID: 24170860 Free PMC article.

6

Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome.

Shao C, Yang B, Wu T, Huang J, Tang P, Zhou Y, Zhou J, Qiu J, Jiang L, Li H, Chen G, Sun H, Zhang Y, Denise A, Zhang DE, Fu XD. Shao C, et al. Among authors: qiu j. Nat Struct Mol Biol. 2014 Nov;21(11):997-1005. doi: 10.1038/nsmb.2906. Epub 2014 Oct 19. Nat Struct Mol Biol. 2014. PMID: 25326705 Free PMC article.

7

RASL-seq for massively parallel and quantitative analysis of gene expression.

Li H, Qiu J, Fu XD. Li H, et al. Among authors: qiu j. Curr Protoc Mol Biol. 2012 Apr;Chapter 4:Unit 4.13.1-9. doi: 10.1002/0471142727.mb0413s98. Curr Protoc Mol Biol. 2012. PMID: 22470064 Free PMC article.

8

Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.

Keshwani MM, Aubol BE, Fattet L, Ma CT, Qiu J, Jennings PA, Fu XD, Adams JA. Keshwani MM, et al. Among authors: qiu j. Biochem J. 2015 Mar 1;466(2):311-22. doi: 10.1042/BJ20141373. Biochem J. 2015. PMID: 25529026 Free PMC article.

9

SRSF2 Is Essential for Hematopoiesis, and Its Myelodysplastic Syndrome-Related Mutations Dysregulate Alternative Pre-mRNA Splicing.

Komeno Y, Huang YJ, Qiu J, Lin L, Xu Y, Zhou Y, Chen L, Monterroza DD, Li H, DeKelver RC, Yan M, Fu XD, Zhang DE. Komeno Y, et al. Among authors: qiu j. Mol Cell Biol. 2015 Sep 1;35(17):3071-82. doi: 10.1128/MCB.00202-15. Epub 2015 Jun 29. Mol Cell Biol. 2015. PMID: 26124281 Free PMC article.

10

RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes.

Wei C, Xiao R, Chen L, Cui H, Zhou Y, Xue Y, Hu J, Zhou B, Tsutsui T, Qiu J, Li H, Tang L, Fu XD. Wei C, et al. Among authors: qiu j. Mol Cell. 2016 Jun 16;62(6):875-889. doi: 10.1016/j.molcel.2016.04.013. Epub 2016 May 19. Mol Cell. 2016. PMID: 27211866 Free PMC article.

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