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The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC.
Takahashi Y, Sheridan P, Niida A, Sawada G, Uchi R, Mizuno H, Kurashige J, Sugimachi K, Sasaki S, Shimada Y, Hase K, Kusunoki M, Kudo S, Watanabe M, Yamada K, Sugihara K, Yamamoto H, Suzuki A, Doki Y, Miyano S, Mori M, Mimori K. Takahashi Y, et al. Among authors: mori m. Ann Oncol. 2015 May;26(5):935-942. doi: 10.1093/annonc/mdv034. Epub 2015 Jan 28. Ann Oncol. 2015. PMID: 25632068 Free article.
The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
Takatsuno Y, Mimori K, Yamamoto K, Sato T, Niida A, Inoue H, Imoto S, Kawano S, Yamaguchi R, Toh H, Iinuma H, Ishimaru S, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Miyano S, Sugihara K, Mori M. Takatsuno Y, et al. Among authors: mori m. Ann Surg Oncol. 2013 Apr;20(4):1395-402. doi: 10.1245/s10434-012-2657-z. Epub 2012 Sep 14. Ann Surg Oncol. 2013. PMID: 22976378
Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer.
Sugimachi K, Niida A, Yamamoto K, Shimamura T, Imoto S, Iinuma H, Shinden Y, Eguchi H, Sudo T, Watanabe M, Tanaka J, Kudo S, Hase K, Kusunoki M, Yamada K, Shimada Y, Sugihara K, Maehara Y, Miyano S, Mori M, Mimori K. Sugimachi K, et al. Among authors: mori m. Ann Surg Oncol. 2014 Dec;21 Suppl 4:S515-21. doi: 10.1245/s10434-013-3468-6. Epub 2014 Jan 6. Ann Surg Oncol. 2014. PMID: 24390711
9,983 results