Darlix JL - Search Results

1

Role of the nucleocapsid domain in HIV-1 Gag oligomerization and trafficking to the plasma membrane: a fluorescence lifetime imaging microscopy investigation.

El Meshri SE, Dujardin D, Godet J, Richert L, Boudier C, Darlix JL, Didier P, Mély Y, de Rocquigny H. El Meshri SE, et al. Among authors: darlix jl. J Mol Biol. 2015 Mar 27;427(6 Pt B):1480-1494. doi: 10.1016/j.jmb.2015.01.015. Epub 2015 Jan 30. J Mol Biol. 2015. PMID: 25644662

2

HIV-1 nucleocapsid protein activates transient melting of least stable parts of the secondary structure of TAR and its complementary sequence.

Bernacchi S, Stoylov S, Piémont E, Ficheux D, Roques BP, Darlix JL, Mély Y. Bernacchi S, et al. Among authors: darlix jl. J Mol Biol. 2002 Mar 29;317(3):385-99. doi: 10.1006/jmbi.2002.5429. J Mol Biol. 2002. PMID: 11922672

3

Destabilization of the HIV-1 complementary sequence of TAR by the nucleocapsid protein through activation of conformational fluctuations.

Azoulay J, Clamme JP, Darlix JL, Roques BP, Mély Y. Azoulay J, et al. Among authors: darlix jl. J Mol Biol. 2003 Feb 21;326(3):691-700. doi: 10.1016/s0022-2836(02)01430-4. J Mol Biol. 2003. PMID: 12581633

4

Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling.

Mekdad HE, Boutant E, Karnib H, Biedma ME, Sharma KK, Malytska I, Laumond G, Roy M, Réal E, Paillart JC, Moog C, Darlix JL, Mély Y, de Rocquigny H. Mekdad HE, et al. Among authors: darlix jl. Retrovirology. 2016 Aug 11;13(1):54. doi: 10.1186/s12977-016-0287-4. Retrovirology. 2016. PMID: 27515235 Free PMC article.

5

Impact of the terminal bulges of HIV-1 cTAR DNA on its stability and the destabilizing activity of the nucleocapsid protein NCp7.

Beltz H, Azoulay J, Bernacchi S, Clamme JP, Ficheux D, Roques B, Darlix JL, Mély Y. Beltz H, et al. Among authors: darlix jl. J Mol Biol. 2003 Apr 18;328(1):95-108. doi: 10.1016/s0022-2836(03)00244-4. J Mol Biol. 2003. PMID: 12684000

6

Role of the structure of the top half of HIV-1 cTAR DNA on the nucleic acid destabilizing activity of the nucleocapsid protein NCp7.

Beltz H, Piémont E, Schaub E, Ficheux D, Roques B, Darlix JL, Mély Y. Beltz H, et al. Among authors: darlix jl. J Mol Biol. 2004 May 7;338(4):711-23. doi: 10.1016/j.jmb.2004.03.019. J Mol Biol. 2004. PMID: 15099739

7

Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis.

Beltz H, Clauss C, Piémont E, Ficheux D, Gorelick RJ, Roques B, Gabus C, Darlix JL, de Rocquigny H, Mély Y. Beltz H, et al. Among authors: darlix jl. J Mol Biol. 2005 May 20;348(5):1113-26. doi: 10.1016/j.jmb.2005.02.042. Epub 2005 Apr 1. J Mol Biol. 2005. PMID: 15854648

8

During the early phase of HIV-1 DNA synthesis, nucleocapsid protein directs hybridization of the TAR complementary sequences via the ends of their double-stranded stem.

Godet J, de Rocquigny H, Raja C, Glasser N, Ficheux D, Darlix JL, Mély Y. Godet J, et al. Among authors: darlix jl. J Mol Biol. 2006 Mar 10;356(5):1180-92. doi: 10.1016/j.jmb.2005.12.038. Epub 2005 Dec 27. J Mol Biol. 2006. PMID: 16406407

9

Investigating the mechanism of the nucleocapsid protein chaperoning of the second strand transfer during HIV-1 DNA synthesis.

Ramalanjaona N, de Rocquigny H, Millet A, Ficheux D, Darlix JL, Mély Y. Ramalanjaona N, et al. Among authors: darlix jl. J Mol Biol. 2007 Dec 7;374(4):1041-53. doi: 10.1016/j.jmb.2007.10.001. Epub 2007 Oct 5. J Mol Biol. 2007. PMID: 18028945

10

Targeting the viral nucleocapsid protein in anti-HIV-1 therapy.

de Rocquigny H, Shvadchak V, Avilov S, Dong CZ, Dietrich U, Darlix JL, Mély Y. de Rocquigny H, et al. Among authors: darlix jl. Mini Rev Med Chem. 2008 Jan;8(1):24-35. doi: 10.2174/138955708783331603. Mini Rev Med Chem. 2008. PMID: 18220982 Review.

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