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13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors.
Saito K, Matsumoto S, Takakusagi Y, Matsuo M, Morris HD, Lizak MJ, Munasinghe JP, Devasahayam N, Subramanian S, Mitchell JB, Krishna MC. Saito K, et al. Among authors: matsumoto s. Clin Cancer Res. 2015 Nov 15;21(22):5073-81. doi: 10.1158/1078-0432.CCR-14-1717. Epub 2015 Feb 11. Clin Cancer Res. 2015. PMID: 25673698 Free PMC article.
Imaging cycling tumor hypoxia.
Matsumoto S, Yasui H, Mitchell JB, Krishna MC. Matsumoto S, et al. Cancer Res. 2010 Dec 15;70(24):10019-23. doi: 10.1158/0008-5472.CAN-10-2821. Cancer Res. 2010. PMID: 21159626 Free PMC article. Review.
Transient decrease in tumor oxygenation after intravenous administration of pyruvate.
Saito K, Matsumoto S, Devasahayam N, Subramanian S, Munasinghe JP, Morris HD, Lizak MJ, Ardenkjaer-Larsen JH, Mitchell JB, Krishna MC. Saito K, et al. Among authors: matsumoto s. Magn Reson Med. 2012 Mar;67(3):801-7. doi: 10.1002/mrm.23065. Epub 2011 Oct 17. Magn Reson Med. 2012. PMID: 22006570 Free PMC article.
EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.
Matsumoto S, Saito K, Yasui H, Morris HD, Munasinghe JP, Lizak M, Merkle H, Ardenkjaer-Larsen JH, Choudhuri R, Devasahayam N, Subramanian S, Koretsky AP, Mitchell JB, Krishna MC. Matsumoto S, et al. Magn Reson Med. 2013 May;69(5):1443-50. doi: 10.1002/mrm.24355. Epub 2012 Jun 12. Magn Reson Med. 2013. PMID: 22692861 Free PMC article.
Magnetic resonance imaging of tumor oxygenation and metabolic profile.
Krishna MC, Matsumoto S, Saito K, Matsuo M, Mitchell JB, Ardenkjaer-Larsen JH. Krishna MC, et al. Among authors: matsumoto s. Acta Oncol. 2013 Oct;52(7):1248-56. doi: 10.3109/0284186X.2013.819118. Epub 2013 Aug 19. Acta Oncol. 2013. PMID: 23957619 Free PMC article. Review.
In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization.
Matsumoto S, Saito K, Takakusagi Y, Matsuo M, Munasinghe JP, Morris HD, Lizak MJ, Merkle H, Yasukawa K, Devasahayam N, Suburamanian S, Mitchell JB, Krishna MC. Matsumoto S, et al. Antioxid Redox Signal. 2014 Sep 10;21(8):1145-55. doi: 10.1089/ars.2013.5725. Epub 2014 Apr 7. Antioxid Redox Signal. 2014. PMID: 24597714 Free PMC article.
Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.
Takakusagi Y, Matsumoto S, Saito K, Matsuo M, Kishimoto S, Wojtkowiak JW, DeGraff W, Kesarwala AH, Choudhuri R, Devasahayam N, Subramanian S, Munasinghe JP, Gillies RJ, Mitchell JB, Hart CP, Krishna MC. Takakusagi Y, et al. Among authors: matsumoto s. PLoS One. 2014 Sep 25;9(9):e107995. doi: 10.1371/journal.pone.0107995. eCollection 2014. PLoS One. 2014. PMID: 25254649 Free PMC article.
5,936 results