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Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, Lac S, Borge L, Roques J, Gayet O, Pinault M, Guimaraes C, Nigri J, Loncle C, Lavaut MN, Garcia S, Tailleux A, Staels B, Calvo E, Tomasini R, Iovanna JL, Vasseur S. Guillaumond F, et al. Among authors: pinault m. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2473-8. doi: 10.1073/pnas.1421601112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675507 Free PMC article.
Cancer cachexia is associated with a decrease in skeletal muscle mitochondrial oxidative capacities without alteration of ATP production efficiency.
Julienne CM, Dumas JF, Goupille C, Pinault M, Berri C, Collin A, Tesseraud S, Couet C, Servais S. Julienne CM, et al. Among authors: pinault m. J Cachexia Sarcopenia Muscle. 2012 Dec;3(4):265-75. doi: 10.1007/s13539-012-0071-9. Epub 2012 May 31. J Cachexia Sarcopenia Muscle. 2012. PMID: 22648737 Free PMC article.
Cardiolipin content is involved in liver mitochondrial energy wasting associated with cancer-induced cachexia without the involvement of adenine nucleotide translocase.
Julienne CM, Tardieu M, Chevalier S, Pinault M, Bougnoux P, Labarthe F, Couet C, Servais S, Dumas JF. Julienne CM, et al. Among authors: pinault m. Biochim Biophys Acta. 2014 May;1842(5):726-33. doi: 10.1016/j.bbadis.2014.02.003. Epub 2014 Feb 15. Biochim Biophys Acta. 2014. PMID: 24534708 Free article.
Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia.
Peyta L, Jarnouen K, Pinault M, Coulouarn C, Guimaraes C, Goupille C, de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S. Peyta L, et al. Among authors: pinault m. Biochim Biophys Acta. 2015 Nov;1851(11):1490-500. doi: 10.1016/j.bbalip.2015.08.008. Epub 2015 Sep 13. Biochim Biophys Acta. 2015. PMID: 26327596 Free article.
85 results